Science in court: the myth of HIV fingerprinting.

Authors: Abecasis AB, Albert J, Geretti AM, Power L, Vandamme AM, Weait M
Journal: The Lancet Infectious Diseases
Link: http://www.sciencedirect.com/science/article/pii/S1473309910702838?np=y

An Editorial in Nature has emphasised the importance of proper scientific validation of forensic methods before their use in court. Classic fingerprinting, DNA fingerprinting, and brain imaging were discussed, and several cases of doubtful interpretation of forensic evidence with potentially incorrect conviction or exoneration of suspects were indicated.
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Molecular Epidemiological Analysis of Paired pol/env Sequences from Portuguese HIV Type 1 Patients

Authors: Abecasis AB, Camacho RJ, Carvalho AP, Costa I, Diogo I, Gomes P, Martins A, Portuguese Hiv-1 Resistance Study Group
Journal: AIDS Research and Human Retroviruses
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=5&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

The advent of new therapeutic approaches targeting env and the search for efficient anti-HIV-1 vaccines make it necessary to identify the number of recombinant forms using genomic regions that were previously not frequently sequenced.
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Randomly amplified polymorphic DNA (RAPD) polymerase chain reaction assay for comparison of Schistosoma mansoni strains sensitive and resistant to praziquantel.

Authors: Afonso A, Belo S, Calado M, Clemente I, Ferreira CC, Ferreira PM, Figueira AR, Grácio MA, Maurício I, Mendes T, Santos R
Journal: Tropical Medicine & International Health
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=2&SID=2CbhBUDoSw8ZkFBEQLW&page=1&doc=1

Authors: Bartenschlager R, Berger C, Bobardt M, Chatterji U, Coelmont L, Gallay P, Hanoulle X, Lim P, Lippens G, Neyts J, Paeshuyse J, Snoeck J, Vliegen I, Vuagniaux G, Vandamme AM
Journal: PLoS One
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=DEB025+(Alisporivir)+Inhibits+Hepatitis+C+Virus+Replication+by+Preventing+a+Cyclophilin+A+Induced+Cis-Trans+Isomerisation+in+Domain+II+of+NS5A

DEB025/Debio 025 (Alisporivir) is a cyclophilin (Cyp)-binding molecule with potent anti-hepatitis C virus (HCV) activity both in vitro and in vivo. It is currently being evaluated in phase II clinical trials. DEB025 binds to CypA, a peptidyl-prolyl cis-trans isomerase which is a crucial cofactor for HCV replication.
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Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains

Amongst the three series of quinazoline derivatives synthesised and studied in this work, some molecules increase the antibiotic susceptibility of Gram-negative bacteria presenting multidrug-resistant phenotypes.
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Science in court: the myth of HIV fingerprinting.

Molecular Epidemiological Analysis of Paired pol/env Sequences from Portuguese HIV Type 1 Patients

Randomly amplified polymorphic DNA (RAPD) polymerase chain reaction assay for comparison of Schistosoma mansoni strains sensitive and resistant to praziquantel.

DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A

Quinazoline derivatives are efficient chemosensitizers of antibiotic activity in Enterobacter aerogenes, Klebsiella pneumoniae and Pseudomonas aeruginosa resistant strains

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