Characterization of Envelope Surface Glycoprotein from HIV-2 Primary Isolates with Different Coreceptor Usage Profile
- Authors: Cerejo P, Santos-Costa Q, Calado M, Espírito-Santo M, Parreira R, Azevedo-Pereira JM
- Publication Year: 2018
- Journal: AIDS Research and Human Retroviruses
- Link: https://www.liebertpub.com/doi/10.1089/aid.2017.0192%20
The main goal of this work was to identify molecular signatures in envelope surface glycoprotein that may be correlated with coreceptor usage by different human immunodeficiency virus (HIV)-2 strains. From inspection of aligned HIV-2 sequences, we verified that V1/V2 region showed the highest degree of amino acid sequence heterogeneity, including polymorphisms in N-linked glycosylation sites, […]
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