GHTM

Global Health and Tropical Medicine

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Home / Research / Cross-cutting issues / Antimicrobial Resistance and Drug Discovery

Antimicrobial Resistance and Drug Discovery

Advance understanding of AMR and accelerate drug discovery through a unified, multidisciplinary strategy.

Connecting molecular, clinical, epidemiological, and policy perspectives, the ARDD will enhance GHTM’s capacity to generate actionable knowledge and evidence-based solutions for combating resistance in bacteria, parasites, and viruses.

A GHTM Antimicrobial Resistance Network (GHTM-AMRN) will be established to promote data sharing and joint analysis across microbial, vector, and human health domains, supporting genomic epidemiology, GWAS, and AI driven prediction of resistance mechanisms. Collaborative research will focus on developing and testing new antimicrobial candidates and repurposed drugs through a GHTM Drug Discovery Hub, combining CADD, Artificial Intelligence (AI) molecular modeling, and in vivo/in vitro infection systems.

PRIME will lead genomic and molecular studies, CTM will evaluate clinical applications, VBD will contribute with vector-pathogen insights, and PPS will assess implementation feasibility and health policy implications. This integrative framework will strengthen pandemic preparedness, treatment innovation, and evidence-based control strategies for tropical and global infectious diseases.

Capacity building and translation will be key pillars of the ARDD CCI. Annual training programs and postgraduate exchanges will promote interdisciplinary skills in diagnostics, resistance mapping, and pharmacological innovation, while South–South collaborations will expand field validation and clinical research capacity, in collaboration with policymakers to align research outputs with One Health-WHO Global AMR Action Plan goals, promoting sustainable innovation and equitable health impact

Recent Highlights

Plenary Meeting brings the GHTM community together to shape its scientific strategy

Posted: 2026-10-07

GHTM researchers and students discuss the 2025–2029 scientific strategy, research performance and key scientific indicators from 2020 to 2025.
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GHTM’s Galleria mellonella Research Hub participates in the 5th Galleria mellonella Workshop 2026

Posted: 2026-10-06

GHTM researchers showcased the Galleria mellonella Research Hub at an international workshop, fostering scientific exchange and new collaborations.
Read More

Cross-cuting Issue Facilitator

Pedro Cravo

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

Contacts

Rua da Junqueira, 100
1349-008 Lisboa
Portugal

+351 213 652 600

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Funding

UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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© Copyright 2026 IHMT-UNL All Rights Reserved.
  • Universidade Nova de Lisboa
  • Fundação para a Ciência e a Tecnologia

    UIDB/04413/2020
    UIDP/04413/2020

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