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Home / Archives for Belo S

Morphological characteristics of Schistosoma mansoni PZQ-resistant and -susceptible strains are different in presence of Praziquantel

  • Autores: Afonso A, Allegretti SM, Anibal FF, Belo S, Carrilho E, Corrêa SAP, de Oliveira RN, Mendes T, Pinto-Almeida A, Tomas A
  • Ano de Publicação: 2016
  • Journal: Frontiers in Microbiology
  • Link: https://www.frontiersin.org/articles/10.3389/fmicb.2016.00594/full

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Sesquiterpenes effects on DNA of Schistosoma mansoni after in vivo treatment

  • Autores: de Oliveira RN, Ferreira PM, Calado M, Belo S, Afonso A, Garcia VL, Oliveira ASS, de Lurdes Sierpe Jeraldo V, dos Santos KR, Allegretti SM
  • Ano de Publicação: 2018
  • Journal: Gene Reports
  • Link: https://www.sciencedirect.com/science/article/pii/S2452014418300372?via%3Dihub

Schistosomiasis is a chronic Neglected Tropical Disease that can be debilitating, particularly children, of tropical and subtropical regions presenting an enormous global health and economic burden. Notoriously for over 30 years, the praziquantel (PZQ) is the only drug used for treatment of disease. For this reason, the search for new schistosomicidal drugs is a priority. […]
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Dirofilaria immitis and Angiostrongylus vasorum: The current situation of two major canine heartworms in Portugal

  • Autores: Alho AM, Meireles J, Schnyder M, Cardoso L, Belo S, Deplazes P, de Carvalho LM
  • Ano de Publicação: 2018
  • Journal: Veterinary Parasitology
  • Link: https://www.sciencedirect.com/science/article/pii/S0304401718300165?via%3Dihub%20

Cardiopulmonary nematodes are life-threatening pet parasites increasingly reported throughout Europe, with overlapping endemic areas. Dirofilaria immitis is a mosquito-borne whilst Angiostrongylus vasorum is a snail-borne pathogen. Both adult nematodes reside in the pulmonary arteries and right cardiac ventricle of domestic and wild canids, causing a wide spectrum of clinical presentations ranging from cough, dyspnoea and […]
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The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype

  • Autores: Afonso A, Armada A, Belo S, Carrilho E, Mendes T, Pinto-Almeida A, Viveiros M
  • Ano de Publicação: 2015
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140147%20

Schistosomiasis is a neglected disease caused by a trematode of the genus Schistosoma that is second only to malaria in public health significance in Africa, South America, and Asia. Praziquantel (PZQ) is the drug of choice to treat this disease due to its high cure rates and no significant side effects. However, in the last […]
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Molecular characterization of Dirofilaria spp. circulating in Portugal

  • Autores: Afonso A, Alho AM, Belo S, Calado M, Ferreira C, Madeira de Carvalho L, Maurício I, Meireles J
  • Ano de Publicação: 2017
  • Journal: Parasites & Vectors
  • Link: https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-017-2180-y

Dirofilariosis is a potentially zoonotic parasitic disease, mainly transmitted by mosquito vectors in many parts of the world. Data concerning the canine Dirofilaria species currently circulating in Portugal is scarce. Thereby, a large-scale study was conducted to determine the Dirofilaria spp. present in Portugal, based on a molecular approach, and also to optimize a reliable […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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1349-008 Lisboa
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+351 213 652 600
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