Rotavirus A infection in pre- and post-vaccine period: Risk factors, genotypes distribution by vaccination status and age of children in Nampula Province, Northern Mozambique (2015-2019)

Authors: Assucênio Chissaque, Adilson Fernando Loforte Bauhofer, Idalécia Cossa-Moiane, Ezequias Sitoe, Benilde Munlela, Eva Dora João, Jerónimo S. Langa, Jorfélia José Chilaúle, Simone Salvador Boene, Marta Cassocera, Esperança Lourenço Guimarães, Timothy A. Kellogg, Luzia Gonçalves, Nilsa de Deus
Publication Year: 2021
Journal: PLoS One, 16(8), art e0255720
Link: https://doi.org/10.1371/journal.pone.0255720

ABSTRACT Mozambique introduced the monovalent rotavirus vaccine (Rotarix®, GSK Biologicals, Rixensart, Belgium) in September 2015. Previous analysis, showed that Nampula province continues reporting a high frequency of Rotavirus A (RVA) infection and the emergence of G9P[6], G9P[4] and G3P[4] genotypes. This analysis aimed to determine the RVA frequency; risk factors; genotype distribution by vaccination status […]
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Covert cases of Severe Acute Respiratory Syndrome Coronavirus 2: An obscure but present danger in regions endemic for Dengue and Chikungunya viruses

Authors: Lorenzzo Lyrio Stringari, Michel Norbim de Souza, Nésio Fernandes de Medeiros Junior, Jaqueline Pegoretti Goulart, Camila Giuberti, Reynaldo Dietze, Rodrigo Ribeiro-Rodrigues
Publication Year: 2021
Journal: PLoS One, 16(1), art e0244937
Link: https://doi.org/10.1371/journal.pone.0244937

The impact of SARS-CoV-2 in regions endemic for both Dengue and Chikungunya is still not fully understood. Considering that symptoms/clinical features displayed during Dengue, Chikungunya and SARS-CoV-2 acute infections are similar, undiagnosed cases of SARS-CoV-2 in co-endemic areas may be more prevalent than expected.
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Prevalence of pfk13 and pfmdr1 polymorphisms in Bounkiling, Southern Senegal

Authors: Ambroise Ahouidi, Rafael Oliveira, Lis Lobo, Cyrille Diedhiou, Souleymane Mboup, Fatima Nogueira
Publication Year: 2021
Journal: PLoS One, 16(3), art e0249357
Link: http://doi.org/10.1371/journal.pone.0249357

ABSTRACT ‘Background:’ Delayed Plasmodium falciparum parasite clearance has been associated with Single Nucleotide Polymorphisms (SNPs) in the kelch protein propeller domain (coded by pfk13 gene). SNPs in the Plasmodium falciparum multidrug resistance gene 1 (pfmdr1) are associated with multi-drug resistance including the combination artemether-lumefantrine. To our knowledge, this is the first work providing information on the prevalence of k13-propeller and pfmdr1 mutations from Sédhiou, […]
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Drivers of HIV-1 transmission: The Portuguese case

Authors: Pineda-Peña AC, Pingarilho M, Li G, Vrancken B, Libin P, Gomes P, Camacho RJ, Theys K, Abecasis AB, Portuguese Hiv-1 Resistance Study Group
Publication Year: 2019
Journal: PLoS One
Link: https://www.ncbi.nlm.nih.gov/pubmed/31568476

BACKGROUND: Portugal has one of the most severe HIV-1 epidemics in Western Europe. Two subtypes circulate in parallel since the beginning of the epidemic. Comparing their transmission patterns and its association with transmitted drug resistance (TDR) is important to pinpoint transmission hotspots and to develop evidence-based treatment guidelines. METHODS: Demographic, clinical and genomic data were […]
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Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Mediterranean region based on mitochondrial sequences

Authors: Bruno de Sousa C, Cox CJ, Brito L, Pavão MM, Pereira H, Ferreira A, Ginja C, Campino L, Bermejo R, Parente M, Varela J
Publication Year: 2019
Journal: PLoS One
Link: https://www.ncbi.nlm.nih.gov/pubmed/30699208

Cystoseira is a common brown algal genus widely distributed throughout the Atlantic and Mediterranean regions whose taxonomical assignment of specimens is often hampered by intra- and interspecific morphological variability. In this study, three mitochondrial regions, namely cytochrome oxidase subunit 1 (COI), 23S rDNA (23S), and 23S-tRNAVal intergenic spacer (mt-spacer) were used to analyse the phylogenetic […]
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Rotavirus A infection in pre- and post-vaccine period: Risk factors, genotypes distribution by vaccination status and age of children in Nampula Province, Northern Mozambique (2015-2019)

Covert cases of Severe Acute Respiratory Syndrome Coronavirus 2: An obscure but present danger in regions endemic for Dengue and Chikungunya viruses

Prevalence of pfk13 and pfmdr1 polymorphisms in Bounkiling, Southern Senegal

Drivers of HIV-1 transmission: The Portuguese case

Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Mediterranean region based on mitochondrial sequences

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