GHTM

Global Health and Tropical Medicine

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Home / Archives for PLoS One

Infection by intestinal parasites, stunting and anemia in school-aged children from southern Angola

  • Authors: Atouguia J, Centeno-Lima S, Ferreira FS, Fortes F, Guerra A, Oliveira D
  • Publication Year: 2015
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137327

Intestinal parasites are responsible for morbidity in children worldwide, especially in low income countries. In the present study we determine the prevalence of intestinal parasites and explore its association with anemia and stunting in school-aged children. A cross-sectional study was conducted from September to October 2010 enrolling 328 children attending the primary school in Lubango, […]
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The role of efflux pumps in Schistosoma mansoni Praziquantel resistant phenotype

  • Authors: Afonso A, Armada A, Belo S, Carrilho E, Mendes T, Pinto-Almeida A, Viveiros M
  • Publication Year: 2015
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140147%20

Schistosomiasis is a neglected disease caused by a trematode of the genus Schistosoma that is second only to malaria in public health significance in Africa, South America, and Asia. Praziquantel (PZQ) is the drug of choice to treat this disease due to its high cure rates and no significant side effects. However, in the last […]
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The effect of ursolic acid on leishmania (Leishmania) amazonensis is related to programed cell death and presents therapeutic potential in experimental cutaneous leishmaniasis

  • Authors: Campos BL, Jesus JA, Kállas EG, Lago JH, Laurenti MD, Levy D, Passero LF, Rafael-Fernandes M, Ribeiro SP, Santos-Gomes G, Sessa DP, Silva MS, Yamamoto ES
  • Publication Year: 2015
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144946%20

Among neglected tropical diseases, leishmaniasis is one of the most important ones, affecting more than 12 million people worldwide. The available treatments are not well tolerated, and present diverse side effects, justifying the search for new therapeutic compounds. In the present study, the activity of ursolic acid (UA) and oleanolic acid (OA) were assayed in […]
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Alterations in evoked otoacoustic emissions by the use of meglumine antimoniate in american tegumentary leishmaniasis patients

  • Authors: Carvalho de Castro E, de Araújo-Melo MH, de Oliveira Schubach A, de Vasconcellos Carvalhães Oliveira R, do Nascimento Brahim Paes LR, Jardim Duarte CC, Oliveira Bezerra DC, Oliveira de Barcelos R, Pereira Bom Braga F, Ramos Ferreira Terceiro B, Salgado de Sousa Torraca T, Valete-Rosalino CM
  • Publication Year: 2017
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168492

Tegumentary Leishmaniasis (TL) is a neglected, non-contagious, infectious disease, caused by different protozoa species of the Leishmania genus that affects skin and mucous membranes. Meglumine Antimoniate (MA), the first drug of choice for TL treatment in Brazil, has already been associated with cochlear toxicity, which is defined as damages of the cochlea caused by exposure to chemical […]
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Characterization of rotavirus infection in children with acute gastroenteritis in Bengo province, Northwestern Angola, prior to vaccine introduction

  • Authors: Brito M, Gasparinho C, Istrate C, Mayer C, Mendes C, Mirante MC, Nery SV, Piedade J
  • Publication Year: 2017
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176046

BACKGROUND: Rotavirus group A (RVA) is considered the leading cause of pediatric diarrhea, responsible for the high burden of diarrheal diseases in sub-Saharan Africa. Despite recent studies, the existent data are scarce for some African countries like Angola, a country with one of the highest RVA-related death estimates. The aim of this study was to […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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