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Home / Archives for Jesus JA

The effect of ursolic acid on leishmania (Leishmania) amazonensis is related to programed cell death and presents therapeutic potential in experimental cutaneous leishmaniasis

  • Autores: Campos BL, Jesus JA, Kállas EG, Lago JH, Laurenti MD, Levy D, Passero LF, Rafael-Fernandes M, Ribeiro SP, Santos-Gomes G, Sessa DP, Silva MS, Yamamoto ES
  • Ano de Publicação: 2015
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144946%20

Among neglected tropical diseases, leishmaniasis is one of the most important ones, affecting more than 12 million people worldwide. The available treatments are not well tolerated, and present diverse side effects, justifying the search for new therapeutic compounds. In the present study, the activity of ursolic acid (UA) and oleanolic acid (OA) were assayed in […]
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Corrigendum to “Therapeutic effect of ursolic acid in experimental visceral leishmaniasis”

  • Autores: Ferreira AF, Fragoso TN, Jesus JA, Lago JHG, Laurenti MD, Passero LFD, Santos-Gomes G, Silva MS, Yamamoto ES
  • Ano de Publicação: 2017
  • Journal: International Journal for Parasitology: Drugs and Drug Resistance
  • Link: https://www.sciencedirect.com/science/article/pii/S2211320716300860

Leishmaniasis is an important neglected tropical disease, affecting more than 12 million people worldwide. The available treatments are not well tolerated and present diverse side effects in patients, justifying the search for new therapeutic compounds. In the present study, the therapeutic potential and toxicity of ursolic acid (UA), isolated from the leaves of Baccharis uncinella C. DC. […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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