The effect of ursolic acid on leishmania (Leishmania) amazonensis is related to programed cell death and presents therapeutic potential in experimental cutaneous leishmaniasis
- Autores: Campos BL, Jesus JA, Kállas EG, Lago JH, Laurenti MD, Levy D, Passero LF, Rafael-Fernandes M, Ribeiro SP, Santos-Gomes G, Sessa DP, Silva MS, Yamamoto ES
- Ano de Publicação: 2015
- Journal: PLoS One
- Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144946%20
Among neglected tropical diseases, leishmaniasis is one of the most important ones, affecting more than 12 million people worldwide. The available treatments are not well tolerated, and present diverse side effects, justifying the search for new therapeutic compounds. In the present study, the activity of ursolic acid (UA) and oleanolic acid (OA) were assayed in […]
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