GHTM

Global Health and Tropical Medicine

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Home / Archives for PLoS One

HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality

  • Authors: Abecasis AB, Couto I, Dias S, Fronteira I, Machado D, Tavares AM, Viveiros M
  • Publication Year: 2017
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185526#

International human migration has been rapidly growing. Migrants coming from low and middle income countries continue to be considerably vulnerable and at higher risk for infectious diseases, namely HIV (Human Immunodeficiency Virus) and tuberculosis (TB). In Europe, the number of patients with HIV-TB co-infection has been increasing and migration could be one of the potential […]
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Epidemic dispersion of HIV and HCV in a population of co-infected Romanian injecting drug users

  • Authors: Abagiu A, Abecasis A, Banica L, Jipa R, Libin P, Neaga E, Nicolae I, Otelea D, Paraschiv S, Pineda-Peña AC, Pingarilho M, Theys K
  • Publication Year: 2017
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185866

Co-infections with HIV and HCV are very frequent among people who inject drugs (PWID). However, very few studies comparatively reconstructed the transmission patterns of both viruses in the same population. We have recruited 117 co-infected PWID during a recent HIV outbreak in Romania. Phylogenetic analyses were performed on HIV and HCV sequences in order to […]
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Is there any difference between the in situ and systemic IL-10 and IFN-ã production when clinical forms of cutaneous sporotrichosis are compared?

  • Authors: Conceição-Silva F, Lyra MR, Morgado FN, Pimentel MI, Schubach AO, Valete-Rosalino CM, Vasconcellos ÉCF
  • Publication Year: 2016
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162764

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Mapping risk of malaria transmission in mainland Portugal using a mathematical modelling approach

  • Authors: Capinha C, Gomes E, Rocha J, Sousa C
  • Publication Year: 2016
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164788

Malaria is currently one of the world´s major health problems. About a half-million deaths are recorded every year. In Portugal, malaria cases were significantly high until the end of the 1950s but the disease was considered eliminated in 1973. In the past few years, endemic malaria cases have been recorded in some European countries. With […]
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Curcumin generates oxidative stress and induces apoptosis in adult schistosoma mansoni worms

  • Authors: Afonso A, Belo S, Cunha WR, Curti C, De Aguiar DP, De Paula RG, Ferreira PM, Magalhães LG, Morais ER, Moscardini MBM, Ouchida AT, Rodrigues V
  • Publication Year: 2016
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167135

Inducing apoptosis is an interesting therapeutic approach to develop drugs that act against helminthic parasites. Researchers have investigated how curcumin (CUR), a biologically active compound extracted from rhizomes of Curcuma longa, affects Schistosoma mansoni and several cancer cell lines. This study evaluates how CUR influences the induction of apoptosis and oxidative stress in couples of […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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