Curcumin generates oxidative stress and induces apoptosis in adult schistosoma mansoni worms
- Authors: Afonso A, Belo S, Cunha WR, Curti C, De Aguiar DP, De Paula RG, Ferreira PM, Magalhães LG, Morais ER, Moscardini MBM, Ouchida AT, Rodrigues V
- Publication Year: 2016
- Journal: PLoS One
- Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167135
Inducing apoptosis is an interesting therapeutic approach to develop drugs that act against helminthic parasites. Researchers have investigated how curcumin (CUR), a biologically active compound extracted from rhizomes of Curcuma longa, affects Schistosoma mansoni and several cancer cell lines. This study evaluates how CUR influences the induction of apoptosis and oxidative stress in couples of […]
Read More