Prevalence of pfk13 and pfmdr1 polymorphisms in Bounkiling, Southern Senegal
- Autores: Ambroise Ahouidi, Rafael Oliveira, Lis Lobo, Cyrille Diedhiou, Souleymane Mboup, Fatima Nogueira
- Ano de Publicação: 2021
- Journal: PLoS One, 16(3), art e0249357
- Link: http://doi.org/10.1371/journal.pone.0249357
ABSTRACT ‘Background:’ Delayed Plasmodium falciparum parasite clearance has been associated with Single Nucleotide Polymorphisms (SNPs) in the kelch protein propeller domain (coded by pfk13 gene). SNPs in the Plasmodium falciparum multidrug resistance gene 1 (pfmdr1) are associated with multi-drug resistance including the combination artemether-lumefantrine. To our knowledge, this is the first work providing information on the prevalence of k13-propeller and pfmdr1 mutations from Sédhiou, […]
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