GHTM

Global Health and Tropical Medicine

  • GHTM
    • Vision
    • Mission
    • Governance
    • Scientific Advisory Board
  • News
    • Outreach
    • Events
      • GHTM Sessions
      • Workshops
    • Articles
    • Jobs
  • Research
    • Cross-cutting issues
      • Global Pathogen Dispersion and Population Mobility
      • Drug Discovery and Drug Resistance
      • Diagnostics
      • Public Health Information
      • Fair Research Partnerships
    • Research Groups
      • PPS – Population health, policies and services
      • THOP – TB, HIV and opportunistic diseases and pathogens
      • VBD – Vector borne diseases and pathogens
      • IHC – Individual health care
    • Research in numbers
      • 2020
      • 2019
      • 2018
      • 2017
    • Projects
      • Ongoing Projects
    • Members
      • Population health, policies and services
        • PPS PhD members
        • PPS non PhD members
      • TB, HIV and opportunistic diseases and pathogens
        • THOP PhD members
        • THOP non PhD members
      • Vector-borne diseases and pathogens
        • VBD PhD members
        • VBD non PhD members
      • Individual Health Care
        • IHC PhD members
        • IHC non PhD members
      • Technical / administrative support
  • Publications
  • Education
    • Master Theses
    • PhD Theses
  • Services
Home / Archives for AIDS Research and Human Retroviruses

HIV and Tuberculosis Co-Infection Among Migrants in Portugal: A Brief Study on Their Sociodemographic, Clinical, and Genomic Characteristics

  • Autores: Ana Maria Tavares, Marta Pingarilho, Judite Batista, Miguel Viveiros, Sónia Dias, Cristina Toscano, Perpetua Gomes, Ana Abecasis
  • Ano de Publicação: 2021
  • Journal: AIDS Research and Human Retroviruses, 37(1), pp 34–37
  • Link: https://doi.org/10.1089/aid.2020.0119

SHORT COMMUNICATION ABSTRACT HIV and tuberculosis (TB) are among the global deadliest diseases. Migrant populations are particularly vulnerable to these infections. Yet, literature is still scarce on the epidemiology of HIV–TB co-infection among migrants. In this study, we characterized native and migrant HIV patients followed in Portuguese hospitals, who were diagnosed with TB, regarding their […]
Ler mais

Accidental father-to-son HIV-1 transmission during the seroconversion period

  • Autores: Abecasis A, Bártolo I, Campos T, Ezeonwumelu IJ, Leitner T, Martin F, Romero-Severson EO, Taveira N
  • Ano de Publicação: 2018
  • Journal: AIDS Research and Human Retroviruses
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/30073842

A 4-year-old child born to an HIV-1 seronegative mother was diagnosed with HIV-1, the main risk factor being transmission from the child’s father who was seroconverting at the time of the child’s birth. In the context of a forensic investigation, we aimed to identify the source of infection of the child and date of the […]
Ler mais

Characterization of Envelope Surface Glycoprotein from HIV-2 Primary Isolates with Different Coreceptor Usage Profile

  • Autores: Cerejo P, Santos-Costa Q, Calado M, Espírito-Santo M, Parreira R, Azevedo-Pereira JM
  • Ano de Publicação: 2018
  • Journal: AIDS Research and Human Retroviruses
  • Link: https://www.liebertpub.com/doi/10.1089/aid.2017.0192%20

The main goal of this work was to identify molecular signatures in envelope surface glycoprotein that may be correlated with coreceptor usage by different human immunodeficiency virus (HIV)-2 strains. From inspection of aligned HIV-2 sequences, we verified that V1/V2 region showed the highest degree of amino acid sequence heterogeneity, including polymorphisms in N-linked glycosylation sites, […]
Ler mais

Sub-Epidemics Explain Localized High Prevalence of Reduced Susceptibility to Rilpivirine in Treatment-Naive HIV-1-Infected Patients: Subtype and Geographic Compartmentalization of Baseline Resistance Mutations

  • Autores: Abecasis AB, Baele G, Camacho RJ, Gomes P, Pineda-Peña AC, Theys K, Van Laethem K, Vandamme AM
  • Ano de Publicação: 2016
  • Journal: AIDS Research and Human Retroviruses
  • Link: https://www.liebertpub.com/doi/abs/10.1089/aid.2015.0095%20

The latest nonnucleoside reverse transcriptase inhibitor (NNRTI) rilpivirine (RPV) is indicated for human immunodeficiency virus type-1 (HIV-1) patients initiating antiretroviral treatment, but the extent of genotypic RPV resistance in treatment-naive patients outside clinical trials is poorly defined. This retrospective observational study of clinical data from Belgium and Portugal evaluates genotypic information from HIV-1 drug-naive patients […]
Ler mais

Novel multiregion hybridization assay for the identification of the most prevalent genetic forms of the human immunodeficiency virus type 1 circulating in Portugal

  • Autores: Esteves A, Freitas FB, Parreira R, Piedade J
  • Ano de Publicação: 2013
  • Journal: AIDS Research and Human Retroviruses
  • Link: http://online.liebertpub.com/doi/abs/10.1089/aid.2012.0025

The most efficient method for HIV-1 genetic characterization involves full-genome sequencing, but the associated costs, technical features, and low throughput preclude it from being routinely used for the analysis of large numbers of viral strains. Multiregion hybridization assays (MHA) represent an alternative for a consistent genetic analysis of large numbers of viral strains. Classically, MHA rely on the amplification by real-time PCR of several regions scattered along the HIV-1 genome, and on their characterization with clade-specific TaqMan probes (also known as hydrolysis probes).
Ler mais

  • 1
  • 2
  • Next Page »

About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

Contacts

Rua da Junqueira, 100
1349-008 Lisboa
Portugal
+351 213 652 600
+351 213 632 105

  • Facebook
  • YouTube

Subscribe Newsletter

  • How to get to GHTM/IHMT
  • GHTM Sessions
  • Research Groups
  • Cross-cutting issues
© Copyright 2023 IHMT-UNL Todos os Direitos Reservados.
  • Universidade Nova de Lisboa
  • Fundação para a Ciência e a Tecnologia

    Project UID/Multi/04413/2013