GHTM

Global Health and Tropical Medicine

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HIV and Tuberculosis Co-Infection Among Migrants in Portugal: A Brief Study on Their Sociodemographic, Clinical, and Genomic Characteristics

SHORT COMMUNICATION ABSTRACT HIV and tuberculosis (TB) are among the global deadliest diseases. Migrant populations are particularly vulnerable to these infections. Yet, literature is still scarce on the epidemiology of HIV–TB co-infection among migrants. In this study, we characterized native and migrant HIV patients followed in Portuguese hospitals, who were diagnosed with TB, regarding their […]
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Genetic lineage characterization and spatiotemporal dynamics of classical insect-specific flaviviruses: outcomes and limitations

HIGHLIGHTS • Complete and partial cISF sequences were characterized using multiple analyses. • cISF sequences show low diversity and entropy, and evolve under purifying selection. • Recombination does not seem to impact the evolution of cISF extensively. • Different datasets displayed high phylogenetic, but mostly low temporal signals. • Spatiotemporal dispersal analyses suggested cISF distribution […]
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Effectiveness of integrase strand transfer inhibitor-based regimens in HIV-infected treatment-naive individuals: results from a European multi-cohort study

ABSTRACT ‘Background:’ INSTIs have become a pillar of first-line ART. Real-world data are needed to assess their effectiveness in routine care. ‘Objectives:’ We analysed ART-naive patients who started INSTI-based regimens in 2012–19 whose data were collected by INTEGRATE, a European collaborative study including seven national cohorts. ‘Methods:’ Kaplan–Meier analyses assessed time to virological failure (VF), […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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