Accidental father-to-son HIV-1 transmission during the seroconversion period

A 4-year-old child born to an HIV-1 seronegative mother was diagnosed with HIV-1, the main risk factor being transmission from the child’s father who was seroconverting at the time of the child’s birth. In the context of a forensic investigation, we aimed to identify the source of infection of the child and date of the […]
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Donor-Recipient Identification in Para- and Poly-phyletic Trees Under Alternative HIV-1 Transmission Hypotheses Using Approximate Bayesian Computation

Authors: Abecasis A, Azevedo-Pereira JM, Bártolo I, Bulla I, Hengartner N, Leitner T, Romero-Severson EO, Taveira N
Publication Year: 2017
Journal: Genetics

Diversity of the founding population of Human Immunodeficiency Virus Type 1 (HIV-1) transmissions raises many important biological, clinical, and epidemiological issues. In up to 40% of sexual infections, there is clear evidence for multiple founding variants. These variants can influence the efficacy of putative prevention methods, and the reconstruction of epidemiologic histories. The authors created an […]
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Accidental father-to-son HIV-1 transmission during the seroconversion period

Donor-Recipient Identification in Para- and Poly-phyletic Trees Under Alternative HIV-1 Transmission Hypotheses Using Approximate Bayesian Computation

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