Optical investigation of medicine solutions in micro-droplets form at interaction with laser radiation.

Authors: Amaral L, Andrei IR, Boni M, Nastasa V, Pascu ML, Staicu A
Journal: Physical Chemistry of Interfaces and Nanomaterials X
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=6&SID=Y2ytOr2frNCuRlReLtM&page=1&doc=1

One of the alternatives to the existing medicines and treatment procedures in fighting multi drug resistance (MDR) is strengthening the effects of medicines by modifying their molecular structures through exposure to laser radiation.
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Duffy negative antigen is no longer a barrier to Plasmodium vivax–molecular evidences from the African West Coast (Angola and Equatorial Guinea)

Authors: Arez AP, Benito A, Berzosa P, Cano J, de Sousa B, Dias F, Do Rosário VE, Figueiredo J, Mendes C, Mora VG
Journal: Plos Neglected Tropical Diseases
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Duffy+negative+antigen+is+no+longer+a+barrier+to+Plasmodium+vivax+%E2%80%93+molecular+evidences+from+the+African+west+coast+(Angola+and+Equatorial+Guinea).

Plasmodium vivax shows a small prevalence in West and Central Africa due to the high prevalence of Duffy negative people. However, Duffy negative individuals infected with P. vivax have been reported in areas of high prevalence of Duffy positive people who may serve as supply of P. vivax strains able to invade Duffy negative erythrocytes. We investigated the presence of P. vivax in two West African countries, using blood samples and mosquitoes collected during two on-going studies.
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The rare HIV-1 gp41 mutations 43T and 50V elevate enfuvirtide resistance levels of common enfuvirtide resistance mutations that did not impact susceptibility to sifuvirtide

Mutations that are selected at low frequency and/or reside outside the enfuvirtide target region, amino acid 36-45 of gp41, might still be important determinants for drug resistance.
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It is anticipated that as is usually the case, financial motivation will move TZ from its current status potential anti-MDR/XDR agent, to one that will cure MDR and XDR TB. Foreword.

Authors: Amaral, Leonard
Journal: Recent Patents on Anti-Infective Drug Discovery
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=4&SID=2CbhBUDoSw8ZkFBEQLW&page=1&doc=1

Authors: Amaral L, Cerca P, Couto I, Fanning S, Machado L, Martins A, Pagès JM, Spengler G, Viveiros M
Journal: International Journal of Antimicrobial Agents
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Ethidium+bromide+efflux+by+Salmonella%3A+modulation+by+metabolic+energy%2C+pH%2C+ions+and+phenothiazines

The main efflux pump of Salmonella enterica serotype Enteritidis, which obtains its energy for the extrusion of noxious agents from the proton-motive force, was studied with the aid of an ethidium bromide (EtBr) semi-automated method under conditions that define the role of metabolic energy, ions and pH in the extrusion of the universal substrate EtBr.
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Optical investigation of medicine solutions in micro-droplets form at interaction with laser radiation.

Duffy negative antigen is no longer a barrier to Plasmodium vivax–molecular evidences from the African West Coast (Angola and Equatorial Guinea)

The rare HIV-1 gp41 mutations 43T and 50V elevate enfuvirtide resistance levels of common enfuvirtide resistance mutations that did not impact susceptibility to sifuvirtide

It is anticipated that as is usually the case, financial motivation will move TZ from its current status potential anti-MDR/XDR agent, to one that will cure MDR and XDR TB. Foreword.

Ethidium bromide efflux by Salmonella: modulation by metabolic energy, pH, ions and phenothiazines

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