Rapid, laser-induced conversion of 20-hydroxyecdysone and its diacetonide — experimental set-up of a system for photochemical transformation of bioactive substances.
- Autores: Alexandru T, Amaral L, Andrei IR, Boni M, Danko B, Hunyadi A, Militaru A, Nastasa V, Pascu ML
- Journal: Anticancer Research
- Link: http://www.ncbi.nlm.nih.gov/pubmed/22493361
Photochemical transformation of certain bioactive compounds for the purpose of obtaining derivatives with increased bioactivity is a prospective area of synthetic chemistry. Ecdysteroids, analogs of the insect molting hormone, which can also exert several beneficial effects in mammals including humans, contain an enone moiety in their B ring, and, as such, are good candidates for photochemical transformations.