GHTM

Global Health and Tropical Medicine

  • GHTM
    • Vision
    • Mission
    • Governance
    • Scientific Advisory Board
  • News
    • Outreach
    • Events
      • GHTM Sessions
      • Workshops
    • Articles
    • Jobs
  • Research
    • Cross-cutting issues
      • Global Pathogen Dispersion and Population Mobility
      • Drug Discovery and Drug Resistance
      • Diagnostics
      • Public Health Information
      • Fair Research Partnerships
    • Research Groups
      • PPS – Population health, policies and services
      • THOP – TB, HIV and opportunistic diseases and pathogens
      • VBD – Vector borne diseases and pathogens
      • IHC – Individual health care
    • Research in numbers
      • 2020
      • 2019
      • 2018
      • 2017
    • Projects
      • Ongoing Projects
    • Members
      • Population health, policies and services
        • PPS PhD members
        • PPS non PhD members
      • TB, HIV and opportunistic diseases and pathogens
        • THOP PhD members
        • THOP non PhD members
      • Vector-borne diseases and pathogens
        • VBD PhD members
        • VBD non PhD members
      • Individual Health Care
        • IHC PhD members
        • IHC non PhD members
      • Technical / administrative support
  • Publications
  • Education
    • Master Theses
    • PhD Theses
  • Services
Home / Archives for de Sousa B

Malaria determining risk factors at the household level in two rural villages of mainland Equatorial Guinea

  • Autores: Guerra M, de Sousa B, Ndong-Mabale N, Berzosa P, Arez AP
  • Ano de Publicação: 2018
  • Journal: Malaria Journal
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/29776367

BACKGROUND: After the introduction of an artemisinin-based combination therapy, the reduction of prevalence of malaria infections has shown a remarkable progress during the last decade. However due to the lack of a consistent malaria control programme and socioeconomic inequalities, Plasmodium infection is still one of the major cause of disease in Equatorial Guinea, namely in […]
Ler mais

Portugal and Angola: Similarities and differences in Toxoplasma gondii seroprevalence and risk factors in pregnant women

  • Autores: de Sousa B, Lobo ML, Matos O, Patrocinio G, Sevivas T
  • Ano de Publicação: 2017
  • Journal: Epidemiology & Infection
  • Link: https://www.cambridge.org/core/journals/epidemiology-and-infection/article/portugal-and-angola-similarities-and-differences-in-toxoplasma-gondii-seroprevalence-and-risk-factors-in-pregnant-women/8ABAD35CD7741CC84F21302DF0BD8531

In this study we determined the presence of IgM/IgG antibodies to Toxoplasma gondii in sera of 155 and 300 pregnant women from Lisbon (Portugal) and Luanda (Angola), respectively, and evaluated the potential risk factors associated with this infection. DNA detection was performed by PCR assays targeting T. gondii regions (RE/B1). Overall, 21·9% (10·9% IgG, 10·9% […]
Ler mais

Plasmodium falciparum genetic diversity in continental Equatorial Guinea before and after introduction of artemisinin based combination therapy

  • Autores: Arez AP, Berzosa P, de Sousa B, Guerra M, Mendes C, Ndong-Mabale N, Neres R, Salgueiro P
  • Ano de Publicação: 2017
  • Journal: Antimicrobial Agents and Chemotherapy
  • Link: http://aac.asm.org/content/61/1/e02556-15.full%20

Efforts to control malaria may affect malaria parasite genetic variability and drug resistance, the latter of which is associated with genetic events that promote mechanisms to escape drug action. The worldwide spread of drug resistance has been a major obstacle to controlling Plasmodium falciparum malaria, and thus the study of the origin and spread of associated mutations […]
Ler mais

Multicentre study highlighting clinical relevance of new high-throughput methodologies in molecular epidemiology of Pneumocystis jirovecii pneumonia

  • Autores: Antunes F, Badura R, Bassat Q, Calderón EJ, de Armas Y, de Sousa B, Esteves F, Huang L, Maltez F, Matos O
  • Ano de Publicação: 2016
  • Journal: Clinical Microbiology and Infection
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/27021425

Pneumocystis jirovecii causes severe interstitial pneumonia (PcP) in immunosuppressed patients. This multicentre study assessed the distribution frequencies of epidemiologically relevant genetic markers of P. jirovecii in different geographic populations from Portugal, the USA, Spain, Cuba and Mozambique, and the relationship between the molecular data and the geographical and clinical information, based on a multifactorial approach. The […]
Ler mais

Highly active ozonides selected against drug resistant malaria

  • Autores: Cabral L, Cristiano MLS, de Sousa B, Lobo L, Nogueira F
  • Ano de Publicação: 2016
  • Journal: Memórias do Instituto Oswaldo Cruz
  • Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957497/

Ever increasing multi-drug resistance by Plasmodium falciparum is creating new challenges in malaria chemotherapy. In the absence of licensed vaccines, treatment and prevention of malaria is heavily dependent on drugs. Potency, range of activity, safety, low cost and ease of administration are crucial issues in the design and formulation of antimalarials. We have tested three synthetic ozonides […]
Ler mais

  • 1
  • 2
  • 3
  • …
  • 5
  • Next Page »

About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

Contacts

Rua da Junqueira, 100
1349-008 Lisboa
Portugal
+351 213 652 600
+351 213 632 105

  • Facebook
  • YouTube

Subscribe Newsletter

  • How to get to GHTM/IHMT
  • GHTM Sessions
  • Research Groups
  • Cross-cutting issues
© Copyright 2023 IHMT-UNL Todos os Direitos Reservados.
  • Universidade Nova de Lisboa
  • Fundação para a Ciência e a Tecnologia

    Project UID/Multi/04413/2013