Highly active ozonides selected against drug resistant malaria
- Authors: Cabral L, Cristiano MLS, de Sousa B, Lobo L, Nogueira F
- Publication Year: 2016
- Journal: Memórias do Instituto Oswaldo Cruz
- Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957497/
Ever increasing multi-drug resistance by Plasmodium falciparum is creating new challenges in malaria chemotherapy. In the absence of licensed vaccines, treatment and prevention of malaria is heavily dependent on drugs. Potency, range of activity, safety, low cost and ease of administration are crucial issues in the design and formulation of antimalarials. We have tested three synthetic ozonides […]
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