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Home / Archives for Calderón EJ

Diversity of Pneumocystis jirovecii Across Europe: A Multicentre Observational Study

  • Autores: Alanio A, Bretagne S, Calderón EJ, Desnos-Ollivier M, Di Cave D, Dupont D, Gits-Muselli M, Guigue N, Hamprecht A, Hauser PM, Helweg-Larsen J, Kicia M, Lagrou K, Lengerova M, Matos O, Melchers WJG, Morio F, Nevez G, Totet A, White LP
  • Ano de Publicação: 2017
  • Journal: EBioMedicine
  • Link: http://www.ebiomedicine.com/article/S2352-3964(17)30262-1/fulltext

Pneumocystis jirovecii is an airborne human-specific ascomycetous fungus responsible for Pneumocystis pneumonia (PCP) in immunocompromised patients, affecting >500,000 patients per year (www.gaffi.org). The understanding of its epidemiology is limited by the lack of standardised culture. Recent genotyping data suggests a limited genetic diversity of P. jirovecii. The objective of the study was to assess the […]
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Multicentre study highlighting clinical relevance of new high-throughput methodologies in molecular epidemiology of Pneumocystis jirovecii pneumonia

  • Autores: Antunes F, Badura R, Bassat Q, Calderón EJ, de Armas Y, de Sousa B, Esteves F, Huang L, Maltez F, Matos O
  • Ano de Publicação: 2016
  • Journal: Clinical Microbiology and Infection
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/27021425

Pneumocystis jirovecii causes severe interstitial pneumonia (PcP) in immunosuppressed patients. This multicentre study assessed the distribution frequencies of epidemiologically relevant genetic markers of P. jirovecii in different geographic populations from Portugal, the USA, Spain, Cuba and Mozambique, and the relationship between the molecular data and the geographical and clinical information, based on a multifactorial approach. The […]
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Diagnosis of Pneumocystis pneumonia: evaluation of four serologic biomarkers

  • Autores: Antunes F, Badura R, Calderón EJ, Calé SS, de Boer MG, Esteves F, Maltez F, Márquez-Martín E, Matos O, van der Reijden TJ
  • Ano de Publicação: 2015
  • Journal: Clinical Microbiology and Infection
  • Link: http://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)00111-6/fulltext%20

The diagnosis of Pneumocystis pneumonia (PCP) relies on microscopic visualization of Pneumocystis jiroveciiorganisms or DNA detection in pulmonary specimens. This study aimed to assess the usefulness of (1–3)-β-d-glucan (BG), Krebs von den Lungen-6 antigen (KL-6), lactate dehydrogenase (LDH) and S-adenosyl methionine (SAM) as serologic biomarkers in the diagnosis of PCP. Serum levels of BG, KL-6, […]
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The 13th International Workshops on Opportunistic Protists (IWOP13)

  • Autores: Calderón EJ, Cushion MT, Kaneshiro ES, Lorenzo-Morales J, Matos O, Weiss LM, Xiao L
  • Ano de Publicação: 2015
  • Journal: Journal of Eukaryotic Microbiology
  • Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564322/%20

The 13th International Workshops on Opportunistic Protists (IWOP-13) was held November 13-15, 2014 in Seville, Spain. The objectives of the IWOP meetings are to: (1) serve as a forum for exchange of new information among active researchers concerning the basic biology, molecular genetics, immunology, biochemistry, pathogenesis, drug development, therapy, and epidemiology of these immunodeficiency-associated pathogenic eukaryotic microorganisms that are seen in patients with AIDS and; (2) to foster the entry of new and young investigators into these underserved research areas.
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The 12th International Workshops on Opportunistic Protists (IWOP-12)

  • Autores: Calderón EJ, Cushion MT, Didier E, Kaneshiro ES, Marciano-Cabral F, Matos O, Sinai AP, Weiss LM, Xiao L
  • Journal: Journal of Eukaryotic Microbiology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23560871

The 12th International Workshops on Opportunistic Protists (IWOP-12) was held in August 2012 in Tarrytown, New York. The objectives of the IWOP meetings are to: (1) serve as a forum for exchange of new information among active researchers concerning the basic biology, molecular genetics, immunology, biochemistry, pathogenesis, drug development, therapy, and epidemiology of these immunodeficiency-associated pathogenic eukaryotic microorganisms that are seen in patients with AIDS and (2) foster the entry of new and young investigators into these underserved research areas.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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