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Global Health and Tropical Medicine

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Home / Archives for Badura R

A case of imported neurocysticercosis in Portugal

  • Autores: Badura R, Beato S, Boura M, Grácio MA, Marques T, Neno M, Neves JC, Sutre AF, Valadas E
  • Ano de Publicação: 2015
  • Journal: The Journal of Infection in Developing Countries
  • Link: https://jidc.org/index.php/journal/article/view/25596581/1240

Neurocysticercosis (NCC) is the most common cause of acquired epilepsy in resource-poor countries. We report the case of a 24-year-old woman born and residing in Guinea-Bissau, who was transferred to Portugal two months after the onset of a possible meningitis (fever, headache, seizures, and coma) that did not respond to antibiotic treatment. The diagnosis of […]
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Multicentre study highlighting clinical relevance of new high-throughput methodologies in molecular epidemiology of Pneumocystis jirovecii pneumonia

  • Autores: Antunes F, Badura R, Bassat Q, Calderón EJ, de Armas Y, de Sousa B, Esteves F, Huang L, Maltez F, Matos O
  • Ano de Publicação: 2016
  • Journal: Clinical Microbiology and Infection
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/27021425

Pneumocystis jirovecii causes severe interstitial pneumonia (PcP) in immunosuppressed patients. This multicentre study assessed the distribution frequencies of epidemiologically relevant genetic markers of P. jirovecii in different geographic populations from Portugal, the USA, Spain, Cuba and Mozambique, and the relationship between the molecular data and the geographical and clinical information, based on a multifactorial approach. The […]
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Diagnosis of Pneumocystis pneumonia: evaluation of four serologic biomarkers

  • Autores: Antunes F, Badura R, Calderón EJ, Calé SS, de Boer MG, Esteves F, Maltez F, Márquez-Martín E, Matos O, van der Reijden TJ
  • Ano de Publicação: 2015
  • Journal: Clinical Microbiology and Infection
  • Link: http://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)00111-6/fulltext%20

The diagnosis of Pneumocystis pneumonia (PCP) relies on microscopic visualization of Pneumocystis jiroveciiorganisms or DNA detection in pulmonary specimens. This study aimed to assess the usefulness of (1–3)-β-d-glucan (BG), Krebs von den Lungen-6 antigen (KL-6), lactate dehydrogenase (LDH) and S-adenosyl methionine (SAM) as serologic biomarkers in the diagnosis of PCP. Serum levels of BG, KL-6, […]
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(1-3)-Beta-D-glucan in association with lactate dehydrogenase as biomarkers of Pneumocystis pneumonia (PcP) in HIV-infected patients

  • Autores: Antunes F, Badura R, de Sousa B, Esteves F, Fernandes C, Gaspar JF, Lee CH, Matos O, Seringa M
  • Ano de Publicação: 2014
  • Journal: European Journal of Microbiology & Infectious Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24487911

Pneumocystis pneumonia (PcP) is a major HIV-related illness caused by Pneumocystis jirovecii. Definitive diagnosis of PcP requires microscopic detection of P. jirovecii in pulmonary specimens. The objective of this study was to evaluate the usefulness of two serum markers in the diagnosis of PcP. Serum levels of (1-3)-beta-d-glucan (BG) and lactate dehydrogenase (LDH) were investigated in 100 HIV-positive adult patients and 50 healthy blood donors.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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1349-008 Lisboa
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+351 213 652 600
+351 213 632 105

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