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Home / Archives for Mora VG

Duffy negative antigen is no longer a barrier to Plasmodium vivax–molecular evidences from the African West Coast (Angola and Equatorial Guinea)

  • Autores: Arez AP, Benito A, Berzosa P, Cano J, de Sousa B, Dias F, Do Rosário VE, Figueiredo J, Mendes C, Mora VG
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Duffy+negative+antigen+is+no+longer+a+barrier+to+Plasmodium+vivax+%E2%80%93+molecular+evidences+from+the+African+west+coast+(Angola+and+Equatorial+Guinea).

Plasmodium vivax shows a small prevalence in West and Central Africa due to the high prevalence of Duffy negative people. However, Duffy negative individuals infected with P. vivax have been reported in areas of high prevalence of Duffy positive people who may serve as supply of P. vivax strains able to invade Duffy negative erythrocytes. We investigated the presence of P. vivax in two West African countries, using blood samples and mosquitoes collected during two on-going studies.
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GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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