GHTM

Global Health and Tropical Medicine

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Home / Archives for Costa I

Characterization of NS5A and NS5B resistance-associated substitutions from genotype 1 hepatitis C virus infected patients in a Portuguese cohort

  • Authors: Brandão R, Marcelino R, Gonçalves F, Diogo I, Carvalho A, Cabanas J, Costa I, Brogueira P, Ventura F, Miranda A, Mansinho K, Gomes P
  • Publication Year: 2018
  • Journal: Viruses
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/29701642

This study is focused on the prevalent NS5 coding region resistance-associated substitutions (RASs) in DAA-naive genotype (GT)1 HCV-infected patients and their potential impact on success rates. Plasma RNA from 81 GT1 HCV-infected patients was extracted prior to an in-house nested RT-PCR of the NS5 coding region, which is followed by Sanger population sequencing. NS5A RASs were present […]
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Molecular Epidemiological Analysis of Paired pol/env Sequences from Portuguese HIV Type 1 Patients

  • Authors: Abecasis AB, Camacho RJ, Carvalho AP, Costa I, Diogo I, Gomes P, Martins A, Portuguese Hiv-1 Resistance Study Group
  • Journal: AIDS Research and Human Retroviruses
  • Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=5&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

The advent of new therapeutic approaches targeting env and the search for efficient anti-HIV-1 vaccines make it necessary to identify the number of recombinant forms using genomic regions that were previously not frequently sequenced.
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Routine screening of harmful microorganisms in beach sands: implications to public health

  • Authors: Brandão J, Carneiro C, Costa I, Cunha M, Duarte A, Faria N, Ferreira FC, Gargaté MJ, Júlio C, Martins ML, Nevers MB, Oleastro M, Rodrigues R, Sabino R, Solo-Gabriele H, Veríssimo C, Viegas C, Whitman RL
  • Publication Year: 2014
  • Journal: Science of the Total Environment
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24355396

Beaches worldwide provide recreational opportunities to hundreds of millions of people and serve as important components of coastal economies. Beach water is often monitored for microbiological quality to detect the presence of indicators of human sewage contamination so as to prevent public health outbreaks associated with water contact
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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