Trends and predictors of transmitted drug resistance (TDR) and clusters with TDR in a local Belgian HIV-1 epidemic

Authors: Albert J, Balotta C, Boucher C, De Munter P, Derdelinckx I, Ferreira F, Gomez-Lopez A, Khouri R, Kostrikis LG, Kücherer C, Li G, Littsola K, Nielsen C, Paredes R, Pineda-Peña AC, Schrooten Y, Stanojevic M, Trovão NS, Van Laethem K, Van Ranst M, Van Wijngaerden E, Vandamme AM, Vercauteren J, Vinken L, Wensing A
Publication Year: 2014
Journal: PLoS One
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101738

We aimed to study epidemic trends and predictors for transmitted drug resistance (TDR) in our region, its clinical impact and its association with transmission clusters. We included 778 patients from the AIDS Reference Center in Leuven (Belgium) diagnosed from 1998 to 2012. Resistance testing was performed using population-based sequencing and TDR was estimated using the WHO-2009 surveillance list.
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Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi and other intestinal parasites in young children in Democratic Republic of São Tomé and Principe

Authors: Antunes F, Augusto J, Ceita J, Codices V, Lobo ML, Matos O, Xiao L
Publication Year: 2014
Journal: PLoS One
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097708

Rare systemic studies concerning prevalence of intestinal parasites in children have been conducted in the second smallest country in Africa, the Democratic Republic of São Tomé and Príncipe. Fecal specimens from 348 children (214 in-hospital attending the Aires de Menezes Hospital and 134 from Agostinho Neto village) in São Tome Island were studied by parasitological and molecular methods.
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Patterns of Transmitted HIV drug resistance in Europe vary by risk group

Authors: Abecasis A, Albert J, Åsjö B, Balotta C, Bergin C, Beshkov D, Boucher C, Camacho R, Clotet B, Frentz D, Griskevicius A, Grossman Z, Hamouda O, Horban A, Jørgensen L, Kolupajeva T, Korn K, Kostrikis L, Kücherer C, Linka KL, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Programme AW, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, van de Vijver D, Vandamme AM, Vercauteren J
Publication Year: 2014
Journal: PLoS One
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094495

In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the risk behaviour reported.
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Novel HIV-1 recombinants spreading across multiple risk groups in the United Kingdom: the identification and phylogeography of Circulating Recombinant Form (CRF) 50_A1D

Authors: Abecasis AB, Ambrose JC, Delpech VC, Fearnhill E, Foster GM, Geretti AM, Hué S, Leigh Brown AJ
Publication Year: 2014
Journal: PLoS One
Link: http://www.ncbi.nlm.nih.gov/pubmed/24454702

An increase in non-B HIV-1 infections among men who have sex with men (MSM) in the United Kingdom (UK) has created opportunities for novel recombinants to arise and become established. We used molecular mapping to characterize the importance of such recombinants to the UK HIV epidemic, in order to gain insights into transmission dynamics that can inform control strategies.
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Direct detection and differentiation of pathogenic Leptospira species using a multi gene targeted real time PCR approach

Authors: Ahmed A, Amaro A, Costa P, Ferreira AS, Harstkeerl RA, Inácio J, Rocha T, Thompson G, Vieira ML
Publication Year: 2014
Journal: PLoS One
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112312

In this work we describe a novel and simple TaqMan-based multi-gene targeted real-time PCR approach able to detect and differentiate Leptospira interrogans, L. kirschneri, L. borgpeteresenii and L. noguchii, which constitute the veterinary most relevant pathogenic species of Leptospira.
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Trends and predictors of transmitted drug resistance (TDR) and clusters with TDR in a local Belgian HIV-1 epidemic

Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi and other intestinal parasites in young children in Democratic Republic of São Tomé and Principe

Patterns of Transmitted HIV drug resistance in Europe vary by risk group

Novel HIV-1 recombinants spreading across multiple risk groups in the United Kingdom: the identification and phylogeography of Circulating Recombinant Form (CRF) 50_A1D

Direct detection and differentiation of pathogenic Leptospira species using a multi gene targeted real time PCR approach

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