Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene
- Autores: Afonso A, Alves AC, Castro H, Lopes D, Neto Z, Rosário VD, Tomás AM
- Journal: Malaria Journal
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Plasmodium+chabaudi+chabaudi+malaria+parasites+can+develop+stable+resistance+to+atovaquone+with+a+mutation+in+the+cytochrome+b+gene
BACKGROUND:
Plasmodium falciparum, has developed resistance to many of the drugs in use. The recommended treatment policy is now to use drug combinations. The atovaquone-proguanil (AP) drug combination, is one of the treatment and prophylaxis options. Atovaquone (ATQ) exerts its action by inhibiting plasmodial mitochondria electron transport at the level of the cytochrome bc1 complex.
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Phaeohyphomycosis caused by Alternaria infectoria presenting as multiple vegetating lesions in a renal transplant patient.
- Autores: Afonso A, Amaro C, Cardoso J, Cunha D, Inácio J, Maduro AP, Martins Mda L, Pinto GM, Vieira MR
- Journal: Revista Iberoamericana De Micologia
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Phaeohyphomycosis+caused+by+Alternaria+infectoria+presenting+as+multiple+vegetating+lesions+in+a+renal+transplant+patient
The genus Alternaria is one of the most common black moulds and appears to be increasing as a causative agent of subcutaneous phaeohyphomycosis, particularly among immunosuppressed patients. A 53-year-old patient who had received a kidney transplant presented with multiple verrucous lesions on the distal extremities.
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Production and characterization of antigens of Fasciola gigantica and its evaluation in the immunodiagnostic of human fascioliasis (Cape Verde).
Randomly amplified polymorphic DNA (RAPD) polymerase chain reaction assay for comparison of Schistosoma mansoni strains sensitive and resistant to praziquantel.
- Autores: Afonso A, Belo S, Calado M, Clemente I, Ferreira CC, Ferreira PM, Figueira AR, Grácio MA, Maurício I, Mendes T, Santos R
- Journal: Tropical Medicine & International Health
- Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=2&SID=2CbhBUDoSw8ZkFBEQLW&page=1&doc=1