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Home / Archives for Maduro AP

Blepharitis due to Cryptococcus neoformans in a cat from northern Portugal

  • Autores: Alves-Pimenta S, Barros J, Cardozo L, Coelho AC, Maduro AP, Maltez L, Pereira MJ, Pimenta P
  • Ano de Publicação: 2015
  • Journal: Journal of Feline Medicine and Surgery Open Reports
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/28491367

Case summary We report a clinical case of blepharitis due to Cryptococcus neoformans yeasts in a 2-year-old stray cat from northern Portugal (Vila Real) without concurrent naso-ocular signs. Ophthalmological examination revealed mucopurulent discharge from an open wound in the right upper and lower lids. Slit-lamp biomicroscopy showed a normal anterior segment, and intraocular pressure was within the normal […]
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HIV/AIDS-Associated Cryptococcosis in Portugal Spanning the Pre- to Post-HAART Era: A Retrospective Assessment at the Genotypic Level Based on URA5-RFLP.

  • Autores: Maduro AP, Gonçalves L, Inácio J, Martins ML, Faria NC, Teles FRR
  • Ano de Publicação: 2015
  • Journal: Current Microbiology
  • Link: https://link.springer.com/article/10.1007%2Fs00284-015-0873-z%20

Cryptococcosis caused by the fungus Cryptococcus neoformans is an opportunistic mycosis, infecting mainly immunodepressed individuals. Molecular epidemiology studies of cryptococcosis in Europe are limited. This paper presents a retrospective study of cryptococcosis in 105 cryptococcal isolates from two hospitals in Lisbon, Portugal, among HIV/AIDS patients, from 1991 to 2007. Among these patients, the number of […]
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Atypical presentation of entomophthoromycosis caused by Conidiobolus coronatus

  • Autores: Araújo C, Bento DP, Faria N, Maduro AP, Mansinho K, Martins Mda L, Tavares R, Ventura F
  • Journal: Medical Mycology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Atypical+presentation+of+entomophthoromycosis+caused+by+Conidiobolus+coronatus

A male patient from Guinea-Bissau was admitted to Egas Moniz Hospital, Lisbon, complaining of fever and exhibiting a productive cough with mucopurulent discharge and weight loss. He had been using empirical medication with dexamethasone to treat his generalized facial swelling.
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Phaeohyphomycosis caused by Alternaria infectoria presenting as multiple vegetating lesions in a renal transplant patient.

  • Autores: Afonso A, Amaro C, Cardoso J, Cunha D, Inácio J, Maduro AP, Martins Mda L, Pinto GM, Vieira MR
  • Journal: Revista Iberoamericana De Micologia
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Phaeohyphomycosis+caused+by+Alternaria+infectoria+presenting+as+multiple+vegetating+lesions+in+a+renal+transplant+patient

The genus Alternaria is one of the most common black moulds and appears to be increasing as a causative agent of subcutaneous phaeohyphomycosis, particularly among immunosuppressed patients. A 53-year-old patient who had received a kidney transplant presented with multiple verrucous lesions on the distal extremities.
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Insights on the genotype distribution among Cryptococcus neoformans and C. gattii Portuguese clinical isolates

  • Autores: Inácio J, Maduro AP, Mansinho K, Martins ML, Meyer W, Silva I, Teles F
  • Ano de Publicação: 2014
  • Journal: Current Microbiology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24077953

This study provides a comprehensive picture of the C. neoformans/C. gattii molecular types most often associated with human cryptococcosis in Portugal and assesses the impact of C. gattii in these infections. One hundred and twenty-two clinical isolates, from distinct patients, were identified as C. neoformans and genotyped by URA5-RFLP, with the molecular types VNI (45.5 %) and VNIII (30.9 %) being the most commonly found ones.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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