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Home / Archives for Faria NC

HIV/AIDS-Associated Cryptococcosis in Portugal Spanning the Pre- to Post-HAART Era: A Retrospective Assessment at the Genotypic Level Based on URA5-RFLP.

  • Autores: Maduro AP, Gonçalves L, Inácio J, Martins ML, Faria NC, Teles FRR
  • Ano de Publicação: 2015
  • Journal: Current Microbiology
  • Link: https://link.springer.com/article/10.1007%2Fs00284-015-0873-z%20

Cryptococcosis caused by the fungus Cryptococcus neoformans is an opportunistic mycosis, infecting mainly immunodepressed individuals. Molecular epidemiology studies of cryptococcosis in Europe are limited. This paper presents a retrospective study of cryptococcosis in 105 cryptococcal isolates from two hospitals in Lisbon, Portugal, among HIV/AIDS patients, from 1991 to 2007. Among these patients, the number of […]
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Enhanced activity of antifungal drugs using natural phenolics against yeast strains of Candida and Cryptococcus.

  • Autores: Campbell BC, Chan KL, Faria NC, Gonçalves LA, Kim JH, Martins Mde L
  • Journal: Letters in Applied Microbiology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Enhanced+activity+of+antifungal+drugs+using+natural+phenolics+against+yeast+strains+of+Candida+and+Cryptococcus

AIMS:
Determine whether certain, natural phenolic compounds enhance activity of commercial antifungal drugs against yeast strains of Candida and Cryptococcus neoformans.
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Enhancement of commercial antifungal agents by Kojic Acid.

  • Autores: Campbell BC, Chan KL, Chang PK, Faria NC, Kim JH, Kim YK, Mahoney N, Martins Mde L
  • Journal: International Journal of Molecular Sciences
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Enhancement+of+Commercial+Antifungal+Agents+by+Kojic+Acid

Natural compounds that pose no significant medical or environmental side effects are potential sources of antifungal agents, either in their nascent form or as structural backbones for more effective derivatives. Kojic acid (KA) is one such compound. It is a natural by-product of fungal fermentation commonly employed by food and cosmetic industries.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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