GHTM

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Home / Archives for Campbell BC

Enhanced activity of antifungal drugs using natural phenolics against yeast strains of Candida and Cryptococcus.

  • Authors: Campbell BC, Chan KL, Faria NC, Gonçalves LA, Kim JH, Martins Mde L
  • Journal: Letters in Applied Microbiology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Enhanced+activity+of+antifungal+drugs+using+natural+phenolics+against+yeast+strains+of+Candida+and+Cryptococcus

AIMS:
Determine whether certain, natural phenolic compounds enhance activity of commercial antifungal drugs against yeast strains of Candida and Cryptococcus neoformans.
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Enhancement of commercial antifungal agents by Kojic Acid.

  • Authors: Campbell BC, Chan KL, Chang PK, Faria NC, Kim JH, Kim YK, Mahoney N, Martins Mde L
  • Journal: International Journal of Molecular Sciences
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Enhancement+of+Commercial+Antifungal+Agents+by+Kojic+Acid

Natural compounds that pose no significant medical or environmental side effects are potential sources of antifungal agents, either in their nascent form or as structural backbones for more effective derivatives. Kojic acid (KA) is one such compound. It is a natural by-product of fungal fermentation commonly employed by food and cosmetic industries.
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Targeting the mitochondrial respiratory chain of Cryptococcus through antifungal chemosensitization: A model for control of non-fermentative pathogens

  • Authors: Campbell BC, Chan KL, Faria NCG, Haff RP, Kim JH, Martins MDL
  • Journal: Molecules
  • Link: http://www.mdpi.com/1420-3049/18/8/8873

Enhanced control of species of Cryptococcus, non-fermentative yeast pathogens, was achieved by chemosensitization through co-application of certain compounds with a conventional antimicrobial drug.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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Funding

UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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