Understanding the bricks to build better surgical oncology unit at Maputo Central Hospital: prevalent surgical cancers and residents knowledge

Authors: Morais A, Come J, Selemane C, Pires G, Tivane A, Cossa M, Tulsidas S, Antunes L, Costa MJ, Sidat M, Martins MRO, Carrilho C, Santos LL
Publication Year: 2019
Journal: The Pan African Medical Journal
Link: http://www.panafrican-med-journal.com/content/article/32/83/full/

Introduction cancer is a growing concern in Mozambique. However, the country has limited facilities and few oncologists. Surgical oncologists are an unmet need. The aim of this study was to assess residents’ knowledge in prevalent cancer domains and to identify and characterize prevalent cancers treated by surgery at Maputo Central Hospital, the largest hospital in […]
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Re-Emerging foci of visceral leishmaniasis in Armenia – first molecular diagnosis of clinical samples

Authors: Sukiasyan A, Keshishyan A, Manukyan D, Melik-Andreasyan G, Atshemyan L, Apresyan H, Strelkova M, Frohme M, Cortes S, Kuhls K
Publication Year: 2019
Journal: Parasitology
Link: https://www.cambridge.org/core/journals/parasitology/article/reemerging-foci-of-visceral-leishmaniasis-in-armenia-first-molecular-diagnosis-of-clinical-samples/3660B1D3BEF8F25D1EA654C99FE4D933

Visceral leishmaniasis (VL) was firstly reported in Armenia in 1913. Following a considerable increase of the number of cases until the mid 1950s, the disease disappeared after 1969 and re-emerged in 1999. Scientific literature about VL in Armenia is available only in Russian or Armenian. This paper presents a historical overview about leishmaniasis in Armenia […]
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Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

Authors: Costa SS, Sobkowiak B, Parreira R, Edgeworth JD, Viveiros M, Clark TG, Couto I
Publication Year: 2019
Journal: Frontiers in Genetics
Link: https://www.ncbi.nlm.nih.gov/pubmed/30687388

NorA is the best studied efflux system of Staphylococcus aureus and therefore frequently used as a model for investigating efflux-mediated resistance in this pathogen. NorA activity is associated with resistance to fluoroquinolones, several antiseptics and disinfectants and several reports have pointed out the role of efflux systems, including NorA, as a first-line response to antimicrobials in S. aureus. […]
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Elucidating in vitro and in vivo phenotypic behaviour of L. infantum/L. major natural hybrids

Authors: Cortes S, Albuquerque-Wendt, Maia C, Carvalho M, Lima IA, de Freitas LAR, Dos-Santos WLC, Campino L
Publication Year: 2019
Journal: Parasitology
Link: https://www.ncbi.nlm.nih.gov/pubmed/30486907

The clinical manifestation and course of Leishmania infections depend on factors such as species, virulence and host-immunity. Although trypanosomatids are considered to have clonal propagation, genetic hybridization has produced successful natural hybrid lineages. Hybrids displaying strong selective advantages may have an impact on pathogenesis and the eco-epidemiology of leishmaniasis. Thus, characterization of phenotypic properties of […]
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Intracellular and extracellular effector activity of mouse neutrophils in response to cutaneous and visceral Leishmania parasites

Authors: Valério-Bolas A, Pereira M, Alexandre-Pires G, Santos-Mateus D, Rodrigues A, Rafael-Fernandes M, Gabriel A, Passero F, Santos-Gomes G
Publication Year: 2019
Journal: Cellular Immunology
Link: https://www.ncbi.nlm.nih.gov/pubmed/30424873

Neutrophils are short-lived phagocytic cells equipped with several receptors for pathogen recognition and phagocytosis and have intracellular and extracellular effector mechanisms that can inactivate pathogens. Leishmaniases are diseases caused by different species of Leishmania that mainly afflicts poorer populations of tropical and subtropical regions and immunocompromised individuals. Thus, the present study aims to investigate the […]
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Understanding the bricks to build better surgical oncology unit at Maputo Central Hospital: prevalent surgical cancers and residents knowledge

Re-Emerging foci of visceral leishmaniasis in Armenia – first molecular diagnosis of clinical samples

Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

Elucidating in vitro and in vivo phenotypic behaviour of L. infantum/L. major natural hybrids

Intracellular and extracellular effector activity of mouse neutrophils in response to cutaneous and visceral Leishmania parasites

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