Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

• Autores: Costa SS, Sobkowiak B, Parreira R, Edgeworth JD, Viveiros M, Clark TG, Couto I
• Ano de Publicação: 2019
• Journal: Frontiers in Genetics
• Link: https://www.ncbi.nlm.nih.gov/pubmed/30687388

NorA is the best studied efflux system of Staphylococcus aureus and therefore frequently used as a model for investigating efflux-mediated resistance in this pathogen. NorA activity is associated with resistance to fluoroquinolones, several antiseptics and disinfectants and several reports have pointed out the role of efflux systems, including NorA, as a first-line response to antimicrobials in S. aureus. […]
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