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Home / Archives for Edgeworth JD

Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

  • Autores: Costa SS, Sobkowiak B, Parreira R, Edgeworth JD, Viveiros M, Clark TG, Couto I
  • Ano de Publicação: 2019
  • Journal: Frontiers in Genetics
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/30687388

NorA is the best studied efflux system of Staphylococcus aureus and therefore frequently used as a model for investigating efflux-mediated resistance in this pathogen. NorA activity is associated with resistance to fluoroquinolones, several antiseptics and disinfectants and several reports have pointed out the role of efflux systems, including NorA, as a first-line response to antimicrobials in S. aureus. […]
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GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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