Elucidating in vitro and in vivo phenotypic behaviour of L. infantum/L. major natural hybrids
- Authors: Cortes S, Albuquerque-Wendt A, Maia C, Carvalho M, Lima IA, de Freitas LAR, Dos-Santos WLC, Campino L
- Publication Year: 2019
- Journal: Parasitology
- Link: https://www.ncbi.nlm.nih.gov/pubmed/30486907
The clinical manifestation and course of Leishmania infections depend on factors such as species, virulence and host-immunity. Although trypanosomatids are considered to have clonal propagation, genetic hybridization has produced successful natural hybrid lineages. Hybrids displaying strong selective advantages may have an impact on pathogenesis and the eco-epidemiology of leishmaniasis. Thus, characterization of phenotypic properties of […]
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