Anopheles gambiae eicosanoids modulate Plasmodium berghei survival from oocyst to salivary gland invasion
- Autores: Custodio A, Ramos S, Silveira H
- Ano de Publicação: 2014
- Journal: Memórias do Instituto Oswaldo Cruz
- Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156460/
Eicosanoids affect the immunity of several pathogen/insect models, but their role on the Anopheles gambiae response to Plasmodium is still unknown. Plasmodium berghei-infected mosquitoes were injected with an eicosanoid biosynthesis inhibitor, indomethacin (IN), or a substrate, arachidonic acid (AA), at day 7 or day 12 post-infection (p.i.).
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