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Home / Archives for Pedrosa P

Gold nanoprobes for multi loci assessment of multi-drug resistant tuberculosis

  • Authors: Baptista PV, Couto I, Machado D, Pedrosa P, Veigas B, Viveiros M
  • Publication Year: 2014
  • Journal: Tuberculosis
  • Link: http://www.sciencedirect.com/science/article/pii/S147297921400002X

Here we extend the Au-nanoprobe approach towards discriminating specific mutations within inhA and rpoB genes in PCR amplified DNA from isolates. Using a multiplex PCR reaction for these two genes, it is possible to assess both loci in parallel, and extend the potential of the Au-nanoprobe method to MDRTB molecular characterization with special application in the most frequent Portuguese genotypes.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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