GHTM

Global Health and Tropical Medicine

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Home / Archives for 2014

Transmission Potential of Antimony-Resistant Leishmania Field Isolates

  • Authors: Ait-Oudhia K, Eddaikra N, Gazanion E, Maia C, Oury B, Pratlong F, Seblova V, Sereno D, Volf P
  • Publication Year: 2014
  • Journal: Antimicrobial Agents and Chemotherapy
  • Link: http://aac.asm.org/content/58/10/6273.full

We studied the development of antimony-resistant Leishmania infantum in natural vectors Lutzomyia longipalpis and Phlebotomus perniciosus to ascertain the risk of parasite transmission by sand flies.
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First Report of Thelazia Callipaeda in red foxes (Vulpes Vulpes) from Portugal

  • Authors: Cardoso L, Catarino AL, Loureiro F, Maia C, Otranto D, Sargo R, Silva F, Valente J
  • Publication Year: 2014
  • Journal: Journal of Zoo and Wildlife Medicine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25000721

The first cases of infection with the eyeworm Thelazia callipaeda (Spirurida, Thelaziidae) in red foxes (Vulpes vulpes) from Portugal are described. Worms were collected from 1 fox (7 worms) in the north and from 2 foxes (10 worms) in the central region of the country.
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Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells

  • Authors: Alexandre-Pires G, Carreira J, Carvalho S, Rodrigues A, Santos-Gomes GM, Teixeira F
  • Publication Year: 2014
  • Journal: Vaccine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24486368

Control of zoonotic visceral leishmaniosis can be achieved using several available drugs. These drugs present high toxicity and require longer treatment regimens which complicate compliance to the treatment. Other control measures directed to the vector or the reservoirs are useful tools to restrain the spreading of this disease but the effects are transitory.
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Trypanosoma cruzi strain Tcl is associated with chronic Chagas disease in the Brazilian Amazon

  • Authors: Barbosa MDV, Barbosa-Ferreira JM, Coelho LI, da Silva GA, de Brito FR, Guerra JAO, Maciel MG, Magalhaes LK, Magalhaes LKC, Monteiro WM, Prestes SR, Santana RAG, Silveira H
  • Publication Year: 2014
  • Journal: Parasites & Vectors
  • Link: http://www.parasitesandvectors.com/content/7/1/267

The aim of this study was to characterize Trypanosoma cruzi in patients with chronic Chagas disease in the State of Amazonas, Brazil.
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Bioinformatics tools for the investigation of viral evolution and molecular epidemiology

  • Authors: Salemi M, Vandamme AM
  • Publication Year: 2014
  • Journal: Infection Genetics and Evolution
  • Link: https://rega.kuleuven.be/cev/avd/files/publications/peer_reviewed/bioinformatics-tools-2010.pdf

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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