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Home / Archives for Infection Genetics and Evolution

On the contribution of Angola to the initial spread of HIV-1

  • Autores: Andrea-Clemencia Pineda-Peña, Jorge Varanda, João Dinis Sousa, Kristof Theys, Inês Bártolo, Thomas Leitner, Nuno Taveira, Anne-Mieke Vandamme, Ana B. Abecasis
  • Ano de Publicação: 2016
  • Journal: Infection Genetics and Evolution, 46(December), pp 219-222
  • Link: https://doi.org/10.1016/j.meegid.2016.08.009

HIGHLIGHTS • We show for the first time the role of Angola in the early spread of the HIV epidemic. • The first introduction of HIV-1 to Angola could have occurred between 1910 and 1940. • Migrations out of Kinshasa were directed to Luanda, as much as to other cities of DRC. • Colonial migration […]
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Insights on the Mycobacterium tuberculosis population structure associated with migrants from Portuguese-speaking countries over a three-year period in Greater Lisbon, Portugal: Implications at the public health level.

  • Autores: Pereira C, Gomes P, Taveira R, Silva C, Maltez F, Macedo R, Costa C, Couvin D, Rastogi N, Viveiros M, Perdigão J, Portugal I
  • Ano de Publicação: 2019
  • Journal: Infection Genetics and Evolution
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/30928606

Tuberculosis among foreign-born patients is a key indicator of country-level epidemiological profiles and, of an increasing concern in Europe given the more intensified migratory waves of refugees. Since Portugal presents a lower immigrant-associated TB incidence rate when compared to other European countries, we sought to characterize the epidemiology and transmission dynamics among the foreign-born population […]
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Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events

  • Autores: Strydom A, João ED, Motanyane L, Nyaga MM, Christiaan Potgieter A, Cuamba A, Mandomando I, Cassocera M, de Deus N, O'Neill HG
  • Ano de Publicação: 2019
  • Journal: Infection Genetics and Evolution
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/30641151

We report the first whole genome constellations of Mozambican rotavirus A strains detected between 2012 and 2013 in the Mavalane General Hospital in Maputo city and Manhiça District Hospital in the Manhiça district. Consensus sequences for ten DS-1-like strains (G2P[4] and G8P[4]) were identified with an Illumina Miseq platform using cDNA prepared from dsRNA extracted […]
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Advances in the molecular diagnosis of tuberculosis: From probes to genomes

  • Autores: Machado D, Couto I, Viveiros M
  • Ano de Publicação: 2019
  • Journal: Infection Genetics and Evolution
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/30508687

Tuberculosis, disease caused by Mycobacterium tuberculosis, is currently the leading cause of death by a single infectious agent worldwide. Early, rapid and accurate identification of M. tuberculosis and the determination of drug susceptibility is essential for the treatment and management of this disease. Tuberculosis diagnosis is mainly based on chest radiography, smear microscopy and bacteriological […]
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Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries

  • Autores: Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, Silva H, Abilleira F, Brum C, Reis AJ, Macedo M, Scaini JL, Silva AB, Esteves L, Macedo R, Maltez F, Clemente S, Coelho E, Viegas S, Rabna P, Rodrigues A, Taveira N, Jordao L, Kritski A, Lapa e Silva JR, Mokrousov I, Couvin D, Rastogi N, Couto I, Pain A, McNerney R, Clark TG, von Groll A, Dalla Costa ER, Rossetti ML, Silva PEA, Viveiros M, Portugal I
  • Ano de Publicação: 2019
  • Journal: Infection Genetics and Evolution
  • Link: https://www.sciencedirect.com/science/article/pii/S1567134818301023?via%3Dihub%20

Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. To address […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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