Whole-genome characterization of G12 rotavirus strains detected in Mozambique reveals a co-infection with a GXP[14] strain of possible animal origin.

Authors: Strydom A, Motanyane L, Nyaga MM, João ED, Cuamba A, Mandomando I, Cassocera M, de Deus N
Publication Year: 2019
Journal: Journal of General Virology
Link: https://www.ncbi.nlm.nih.gov/pubmed/31140967

A high prevalence of G12 rotavirus strains has previously been reported in southern Mozambique. In this study, the full genomes of five Mozambican G12 strains were determined directly from stool using an Illumina Miseq platform. One sample (0060) contained an intergenogroup co-infection of a G12P[8] Wa-like strain and a GXP[14] DS-1-like strain. The sequences of […]
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Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events

Authors: Strydom A, João ED, Motanyane L, Nyaga MM, Christiaan Potgieter A, Cuamba A, Mandomando I, Cassocera M, de Deus N, O'Neill HG
Publication Year: 2019
Journal: Infection Genetics and Evolution
Link: https://www.ncbi.nlm.nih.gov/pubmed/30641151

We report the first whole genome constellations of Mozambican rotavirus A strains detected between 2012 and 2013 in the Mavalane General Hospital in Maputo city and Manhiça District Hospital in the Manhiça district. Consensus sequences for ten DS-1-like strains (G2P[4] and G8P[4]) were identified with an Illumina Miseq platform using cDNA prepared from dsRNA extracted […]
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Rotavirus A strains obtained from children with acute gastroenteritis in Mozambique, 2012-2013: G and P genotypes and phylogenetic analysis of VP7 and partial VP4 genes

Authors: Acácio S, Cassocera M, Cuamba A, de Deus N, João ED, Mandomando I, Motanyane L, O'Neill HG, Page N, Strydom A
Publication Year: 2017
Journal: Archives of Virology
Link: https://www.ncbi.nlm.nih.gov/pubmed/29052059

In Mozambique rotavirus (RV) was shown to be the greatest cause of acute diarrhoea in infants from 0 to 11 months, and in 2015, national rotavirus vaccination was introduced. As with other developing countries, there is very limited active strain characterisation. Rotavirus positive clinical specimens, collected between 2012 and 2013, have now provided information on the […]
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Early impact of rotavirus vaccination in children less than five years of age in Mozambique

Authors: Anapakala E, Bambo M, Bero DM, Cassocera M, Chilaúle JJ, Chissaque A, Cossa-Moiane I, de Deus N, Guimarães EL, João ED, Langa JS, Mwenda JM, Parashar UD, Sambo J, Sitoe E, Tate JE, Weldegebriel GG
Publication Year: 2017
Journal: Vaccine
Link: https://www.ncbi.nlm.nih.gov/pubmed/?term=Bero%20DM%5BAuthor%5D&cauthor=true&cauthor_uid=29128381

Mozambique introduced rotavirus vaccine (Rotarix, GSK Biologicals) in the National Immunization Program in September 2015 with the objective of reducing the burden of total diarrheal disease and specifically severe rotavirus disease. This study aimed to evaluate the early impact of rotavirus vaccine in reducing all-cause diarrhea and rotavirus-specific hospitalizations. We analysed stool specimens collected from […]
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Whole-genome characterization of G12 rotavirus strains detected in Mozambique reveals a co-infection with a GXP[14] strain of possible animal origin.

Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events

Rotavirus A strains obtained from children with acute gastroenteritis in Mozambique, 2012-2013: G and P genotypes and phylogenetic analysis of VP7 and partial VP4 genes

Early impact of rotavirus vaccination in children less than five years of age in Mozambique

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