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Global Health and Tropical Medicine

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Home / Archives for Kritski A

Genetic diversity and molecular epidemiology of mycobacterium tuberculosis in Roraima State, Brazil

  • Autores: Tatara MB, Perdigão J, Viveiros M, Kritski A, Silva KED, Sacchi FPC, de Lima CC, Dos Santos PCP, Diniz JLDCG, Almeida Silva PE, Gomes P, Gomes MMQ, Cunha EAT, Lapa e Silva JR, Portugal I, Croda J, Andrade MKN
  • Ano de Publicação: 2019
  • Journal: The American Journal of Tropical Medicine and Hygiene
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/31392954

National border areas are special places for the spread of Mycobacterium tuberculosis (MTB). These regions concentrate vulnerable populations and constant population movements. Understanding the dynamics of the transmission of MTB is fundamental to propose control measures and to monitor drug resistance. We conducted a population-based prospective study of tuberculosis (TB) to evaluate molecular characteristics of MTB isolates […]
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Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries

  • Autores: Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, Silva H, Abilleira F, Brum C, Reis AJ, Macedo M, Scaini JL, Silva AB, Esteves L, Macedo R, Maltez F, Clemente S, Coelho E, Viegas S, Rabna P, Rodrigues A, Taveira N, Jordao L, Kritski A, Lapa e Silva JR, Mokrousov I, Couvin D, Rastogi N, Couto I, Pain A, McNerney R, Clark TG, von Groll A, Dalla Costa ER, Rossetti ML, Silva PEA, Viveiros M, Portugal I
  • Ano de Publicação: 2019
  • Journal: Infection Genetics and Evolution
  • Link: https://www.sciencedirect.com/science/article/pii/S1567134818301023?via%3Dihub%20

Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable gap in the knowledge on the Mycobacterium tuberculosis population structure and strain circulation between the countries still exists. To address […]
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Detection of tuberculosis drug resistance a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus

  • Autores: Anthony RM, Barcellos RB, Bergval I, Costa ERD, Esteves LS, Kritski A, Nunes LS, Oliveira MM, Ramalho DM, Rodenbusch R, Rossetti ML, Santos PFGD, Sengstake S, Viveiros M
  • Ano de Publicação: 2017
  • Journal: Memórias do Instituto Oswaldo Cruz
  • Link: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000600396&lng=en&tlng=en

To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB), new molecular methods that can routinely be used to screen for a wide range of drug resistance related genetic markers in the Mycobacterium tuberculosis genome are urgently needed. To evaluate the performance of multiplex ligaton-dependent probe amplification (MLPA) against Genotype® MTBDRplus to detect resistance to isoniazid […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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+351 213 652 600
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