Detection of tuberculosis drug resistance a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus
- Autores: Anthony RM, Barcellos RB, Bergval I, Costa ERD, Esteves LS, Kritski A, Nunes LS, Oliveira MM, Ramalho DM, Rodenbusch R, Rossetti ML, Santos PFGD, Sengstake S, Viveiros M
- Ano de Publicação: 2017
- Journal: Memórias do Instituto Oswaldo Cruz
- Link: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000600396&lng=en&tlng=en
To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB), new molecular methods that can routinely be used to screen for a wide range of drug resistance related genetic markers in the Mycobacterium tuberculosis genome are urgently needed. To evaluate the performance of multiplex ligaton-dependent probe amplification (MLPA) against Genotype® MTBDRplus to detect resistance to isoniazid […]
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