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Home / Archives for Santana RAG

Anopheles aquasalis transcriptome reveals autophagic responses to Plasmodium vivax midgut invasion

  • Autores: Santana RAG, Oliveira MC, Cabral I, Junior RCAS, de Sousa DRT, Ferreira L, Lacerda MVG, Monteiro WM, Abrantes P, Guerra MDGVB, Silveira H
  • Ano de Publicação: 2019
  • Journal: Parasites & Vectors
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/31126324

BACKGROUND: Elimination of malaria depends on mastering transmission and understanding the biological basis of Plasmodium infection in the vector. The first mosquito organ to interact with the parasite is the midgut and its transcriptomic characterization during infection can reveal effective antiplasmodial responses able to limit the survival of the parasite. The vector response to Plasmodium […]
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Oral transmission of Trypanosoma cruzi, Brazilian Amazon

  • Autores: Santana RAG, Guerra MGVB, Sousa DR, Couceiro K, Ortiz JV, Oliveira M, Ferreira LS, Souza KR, Tavares IC, Morais RF, Silva GAV, Melo GC, Vergel GM, Albuquerque BC, Arcanjo ARL, Monteiro WM, Ferreira JMBB, Lacerda MVG, Silveira H, Guerra JAO
  • Ano de Publicação: 2019
  • Journal: Emerging Infectious Diseases
  • Link: https://wwwnc.cdc.gov/eid/article/25/1/18-0646_article

In the Brazilian Amazon, the suspected source of infection in an outbreak of acute Chagas disease involving 10 patients was Euterpe oleracea (açaí berry) juice. Patient blood and juice samples contained Trypanosoma cruzi TcIV, indicating oral transmission of the Chagas disease agent. © 2018, Centers for Disease Control and Prevention (CDC). All rights reserved.
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Fresh-blood-free diet for rearing malaria mosquito vectors

  • Autores: Cardoso JCR, Felix RC, Guerra MGB, Marques J, Power D, Santana RAG, Silveira H
  • Ano de Publicação: 2018
  • Journal: Scientific Reports
  • Link: https://www.nature.com/articles/s41598-018-35886-3

Mosquito breeding depends on the supply of fresh vertebrate blood, a major bottleneck for large-scale production of Anopheles spp. Feeding alternatives to fresh blood are thus a priority for research, outdoor large-cage trials and control interventions. Several artificial meal compositions were tested and Anopheles oogenesis, egg laying and development into the next generation of adult mosquitoes were followed. We […]
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Trypanosoma cruzi strain Tcl is associated with chronic Chagas disease in the Brazilian Amazon

  • Autores: Barbosa MDV, Barbosa-Ferreira JM, Coelho LI, da Silva GA, de Brito FR, Guerra JAO, Maciel MG, Magalhaes LK, Magalhaes LKC, Monteiro WM, Prestes SR, Santana RAG, Silveira H
  • Ano de Publicação: 2014
  • Journal: Parasites & Vectors
  • Link: http://www.parasitesandvectors.com/content/7/1/267

The aim of this study was to characterize Trypanosoma cruzi in patients with chronic Chagas disease in the State of Amazonas, Brazil.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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