Anopheles aquasalis transcriptome reveals autophagic responses to Plasmodium vivax midgut invasion

Authors: Santana RAG, Oliveira MC, Cabral I, Junior RCAS, de Sousa DRT, Ferreira L, Lacerda MVG, Monteiro WM, Abrantes P, Guerra MDGVB, Silveira H
Publication Year: 2019
Journal: Parasites & Vectors
Link: https://www.ncbi.nlm.nih.gov/pubmed/31126324

BACKGROUND: Elimination of malaria depends on mastering transmission and understanding the biological basis of Plasmodium infection in the vector. The first mosquito organ to interact with the parasite is the midgut and its transcriptomic characterization during infection can reveal effective antiplasmodial responses able to limit the survival of the parasite. The vector response to Plasmodium […]
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Oral transmission of Trypanosoma cruzi, Brazilian Amazon

Authors: Santana RAG, Guerra MGVB, Sousa DR, Couceiro K, Ortiz JV, Oliveira M, Ferreira LS, Souza KR, Tavares IC, Morais RF, Silva GAV, Melo GC, Vergel GM, Albuquerque BC, Arcanjo ARL, Monteiro WM, Ferreira JMBB, Lacerda MVG, Silveira H, Guerra JAO
Publication Year: 2019
Journal: Emerging Infectious Diseases
Link: https://wwwnc.cdc.gov/eid/article/25/1/18-0646_article

In the Brazilian Amazon, the suspected source of infection in an outbreak of acute Chagas disease involving 10 patients was Euterpe oleracea (açaí berry) juice. Patient blood and juice samples contained Trypanosoma cruzi TcIV, indicating oral transmission of the Chagas disease agent. © 2018, Centers for Disease Control and Prevention (CDC). All rights reserved.
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In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate

Authors: Cravo P, Machado RB, Leite JA, Leda T, Suwanarusk R, Bittencourt N, Albrecht L, Judice C, Lopes SCP, Lacerda MVG, Ferreira MU, Soares IS, Goh YS, Bargieri DY, Nosten F, Russell B, Rénia L, Costa FTM
Publication Year: 2018
Journal: Malaria Journal
Link: https://malariajournal.biomedcentral.com/articles/10.1186/s12936-017-2144-x%20

BACKGROUND: Technical limitations for culturing the human malaria parasite Plasmodium vivax have impaired the discovery of vaccine candidates, challenging the malaria eradication agenda. The immunogenicity of the M2 domain of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) antigen cloned from the Plasmodium yoelii murine parasite, has been previously demonstrated. RESULTS: Detailed epitope mapping of MAEBL […]
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Anopheles aquasalis transcriptome reveals autophagic responses to Plasmodium vivax midgut invasion

Oral transmission of Trypanosoma cruzi, Brazilian Amazon

In silico epitope mapping and experimental evaluation of the Merozoite Adhesive Erythrocytic Binding Protein (MAEBL) as a malaria vaccine candidate

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