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Home / Archives for Marques J

Fresh-blood-free diet for rearing malaria mosquito vectors

  • Authors: Cardoso JCR, Felix RC, Guerra MGB, Marques J, Power D, Santana RAG, Silveira H
  • Publication Year: 2018
  • Journal: Scientific Reports
  • Link: https://www.nature.com/articles/s41598-018-35886-3

Mosquito breeding depends on the supply of fresh vertebrate blood, a major bottleneck for large-scale production of Anopheles spp. Feeding alternatives to fresh blood are thus a priority for research, outdoor large-cage trials and control interventions. Several artificial meal compositions were tested and Anopheles oogenesis, egg laying and development into the next generation of adult mosquitoes were followed. We […]
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Microencapsulation of citronella oil for solar-activated controlled release as an insect repellent

  • Authors: Alves GM, Andrade L, Azenha C, Forte M, Marques J, Mendes A, Oliveira C, Parpot P, Pereira AI, Ribeiro AR, Sousa CA, Tavares CJ
  • Publication Year: 2016
  • Journal: Applied Materials
  • Link: https://www.sciencedirect.com/science/article/pii/S235294071630138X

This study investigates the functionalization of titanium dioxide nanoparticles on the surface of polymeric microcapsules as a mean to control the release of encapsulated citronella through solar radiation. This allows for the release of a mosquito repellent without human intervention, as the sunlight works as a release activator. The TiO2 nanoparticles were synthetized using a […]
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Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery

  • Authors: Baró E, Cisteró P, de Paz JL, Delves M, Fernàndez-Busquets X, García-Salcedo JA, Grandfils C, Marques J, Mayor A, Prohens R, Sinden RE, Urbán P, Valle-Delgado JJ
  • Publication Year: 2017
  • Journal: Nanomedicine
  • Link: http://www.nanomedjournal.com/article/S1549-9634(16)30162-9/fulltext

The adaptation of existing antimalarial nanocarriers to new Plasmodium stages, drugs, targeting molecules, or encapsulating structures is a strategy that can provide new nanotechnology-based, cost-efficient therapies against malaria. We have explored the modification of different liposome prototypes that had been developed in our group for the targeted delivery of antimalarial drugs to Plasmodium-infected red blood […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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