GHTM

Global Health and Tropical Medicine

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Home / Publications

Progressive disseminated histoplasmosis as a presentation of AIDS in a patient from the Congo: the role of skin biopsy

  • Authors: Borges-Costa J, Marques T, Sacramento-Marques M, Soares-Almeida L
  • Journal: Tropical Doctor
  • Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=35&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

Progressive disseminated histoplasmosis is frequently fatal in HIV patients, and the standard diagnostic techniques can cause treatment delay. Skin biopsy can help in the differential diagnosis, allowing also an earlier treatment initiation.
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Cellular HIV-1 DNA levels in drug sensitive strains are equivalent to those in drug resistant strains in newly-diagnosed patients in Europe

  • Authors: Balotta C, Clotet B, Demetriou VL, Grossman Z, Jørgensen LB, Kostrikis LG, Kousiappa I, Lepej SZ, Levy I, Nielsen C, Paraskevis D, Poljak M, Roman F, Ruiz L, Schmidt JC, Van de Vijver DA, Vercauteren J, Vandamme AM, Van Laethem K
  • Journal: PLoS One
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/20544014

BACKGROUND:
HIV-1 genotypic drug resistance is an important threat to the success of antiretroviral therapy and transmitted resistance has reached 9% prevalence in Europe. Studies have demonstrated that HIV-1 DNA load in peripheral blood mononuclear cells (PBMC) have a predictive value for disease progression, independently of CD4 counts and plasma viral load.
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Comparative performance of the REGA subtyping tool version 2 versus version 1

  • Authors: Abecasis AB, Camacho RJ, De Oliveira T, Imbrechts S, Libin P, Vandamme AM, Wang Y
  • Journal: Infection Genetics and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Comparative+performance+of+the+REGA+subtyping+tool+version+2+versus+version+1

The REGA HIV-1 subtyping tool is a phylogenetic-based method for subtyping HIV-1 genomic sequences that was published in 2005. The subtyping tool combines phylogenetic approaches with recombination detection methods.
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Scaling-up the medical work- force in Timor-Leste: Challenges of a great leap forward

  • Authors: Buchan J, Cabral J, Dussault G, Ferrinho P
  • Publication Year: 2013
  • Journal: Social Science & Medicine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23932856

The health services system of Timor-Leste (T-L) will, by 2015, add 800 physicians, most of them trained in Cuba, to the 233 employed by the national health system in 2010-2011. The need for more physicians is not in discussion: poor health indicators, low coverage and utilization of services, and poor quality of services are well documented in T-L.
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Mechanisms of fluoroquinolone resistance in Escherichia coli isolates from food-producing animals.

  • Authors: Fanning S, Karczmarczyk M, Leonard N, Martins M, Quinn T
  • Journal: Applied and Environmental Microbiology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/21856834

Eleven multidrug-resistant Escherichia coli isolates (comprising 6 porcine and 5 bovine field isolates) displaying fluoroquinolone (FQ) resistance were selected from a collection obtained from the University Veterinary Hospital (Dublin, Ireland). MICs of nalidixic acid and ciprofloxacin were determined by Etest.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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