Prediction of response to antiretroviral therapy by human experts and by the EuResist data-driven expert system (the EVE study).
- Autores: Altmann A, Boucher CA, Brun-Vezinet F, Harrigan PR, Incardona F, Kaiser R, Lengauer T, Morris L, Obermeier M, Peres Y, Perno CF, Petroczi A, Phanuphak P, Pillay D, Prosperi M, Rosen-Zvi M, Schülter E, Shafer RW, Sönnerborg A, Struck D, Wensing AMJ, Zazzi M, Vandamme AM, Van Laethem K
- Journal: HIV Medicine
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Prediction+of+response+to+antiretroviral+therapy+by+human+experts+and+by+the+EuResist+data-driven+expert+system+(the+EVE+study).
The EuResist expert system is a novel data-driven online system for computing the probability of 8-week success for any given pair of HIV-1 genotype and combination antiretroviral therapy regimen plus optional patient information. The objective of this study was to compare the EuResist system vs. human experts (EVE) for the ability to predict response to treatment.