Comparison of HIV-1 Genotypic Resistance Test Interpretation Systems in Predicting Virological Outcomes Over Time
- Authors: Assel M, Boucher CA, De Luca A, Fabbiani M, Frentz D, Incardona F, Manca N, Müller V, O Nualláin B, Paredes R, Prosperi M, Quiros-Roldan E, Ruiz L, Sloot PM, Torti C, Van de Vijver DA, Zazzi M, Libin P, Vandamme AM, Van Laethem K
- Journal: PLoS One
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Comparison+of+HIV-1+Genotypic+Resistance+Test+Interpretation+Systems+in+Predicting+Virological+Outcomes+Over+Time
BACKGROUND: Several decision support systems have been developed to interpret HIV-1 drug resistance genotyping results. This study compares the ability of the most commonly used systems (ANRS, Rega, and Stanford’s HIVdb) to predict virological outcome at 12, 24, and 48 weeks. METHODOLOGY/PRINCIPAL FINDINGS: Included were 3763 treatment-change episodes (TCEs) for which a HIV-1 genotype was […]
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