Participation of leukotrienes in the immune modulation of oral tolerance

Authors: Afonso A, Carrilho E, de Freitas Anibal F, de Matos AP, de Oliveira SR, Faccioli LH, Frantz FG, Nomizo A
Publication Year: 2017
Journal: Frontiers in Microbiology
Link: https://www.frontiersin.org/articles/10.3389/fmicb.2017.00242/full

Oral tolerance (OT) is characterized as a peripheral immune tolerance form, in which, mature lymphocytes in lymphoid tissues associated with mucosa, become non-functional or hypo responsive due to prior oral administration of antigen. OT is an important immunological phenomenon due to its therapeutic potential in inflammatory processes and others diseases. Here we evaluated leukotriene role […]
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Characterization of an insect-specific flavivirus (OCFVPT) co-isolated from Ochlerotatus caspius collected in southern Portugal along with a putative new Negev-like virus

Authors: Abecasis A, de Almeida AP, de Matos AP, Esteves A, Lopes A, Parreira R, Piedade J
Publication Year: 2013
Journal: Virus Genes
Link: http://www.ncbi.nlm.nih.gov/pubmed/23877720

We describe the isolation and characterization of an insect-specific flavivirus (ISF) from Ochlerotatus caspius (Pallas, 1771) mosquitoes collected in southern Portugal. The RNA genome of this virus, tentatively designated OCFVPT, for O. caspius flavivirus from Portugal, encodes a polyprotein showing all the features expected for a flavivirus. As frequently observed for ISF, the viral genomes seems to encode a putative Fairly Interesting Flavivirus ORF (FIFO)-like product, the synthesis of which would occur as a result of a -1 translation frameshift event. OCFVPT was isolated in the C6/36 Stegomyia albopicta (= Aedes albopictus) cell line where it replicates rapidly, but failed to replicate in Vero cells in common with other ISFs.
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Genetic characterization of an insect-specific flavivirus isolated from Culex theileri mosquitoes collected in southern Portugal.

Authors: Cook S, de Almeida AP, de Matos AP, Esteves A, Lopes A, Parreira R, Piedade J
Journal: Virus Research
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Genetic+characterization+of+an+insect-specific+flavivirus+isolated+from+Culex+theileri+mosquitoes+collected+in+southern+Portugal

We describe the full genetic characterization of an insect-specific flavivirus (ISF) from Culex theileri (Theobald) mosquitoes collected in Portugal. This represents the first isolation and full characterization of an ISF from Portuguese mosquitoes. The virus, designated CTFV, for Culex theileri flavivirus, was isolated in the C6/36 Stegomyia albopicta (=Aedes albopictus) cell line, and failed to replicate in vertebrate (Vero) cells in common with other ISFs.
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Negeviruses found in multiple species of mosquitoes from southern Portugal: Isolation, genetic diversity, and replication in insect cell culture

Authors: Abecasis A, Carapeta S, de Almeida AP, de Matos AP, do Bem B, Esteves A, Lopes A, McGuinness J, Parreira R, Piedade J
Publication Year: 2015
Journal: Virology
Link: https://www.sciencedirect.com/science/article/pii/S0042682215002329%20

In this report, an RT-PCR approach based on the use of degenerate primers allowed the identification of negeviruses in four different species of mosquitoes (Ochlerotatus caspius, Culex pipiens, Cx. theileri and Cx. univittatus) collected in southern Portugal. The genomes of two of these viruses, sequenced to full completion, were shown to encode all the proteins […]
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Participation of leukotrienes in the immune modulation of oral tolerance

Characterization of an insect-specific flavivirus (OCFVPT) co-isolated from Ochlerotatus caspius collected in southern Portugal along with a putative new Negev-like virus

Genetic characterization of an insect-specific flavivirus isolated from Culex theileri mosquitoes collected in southern Portugal.

Negeviruses found in multiple species of mosquitoes from southern Portugal: Isolation, genetic diversity, and replication in insect cell culture

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