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Home / Archives for Faccioli LH

Participation of leukotrienes in the immune modulation of oral tolerance

  • Authors: Afonso A, Carrilho E, de Freitas Anibal F, de Matos AP, de Oliveira SR, Faccioli LH, Frantz FG, Nomizo A
  • Publication Year: 2017
  • Journal: Frontiers in Microbiology
  • Link: https://www.frontiersin.org/articles/10.3389/fmicb.2017.00242/full

Oral tolerance (OT) is characterized as a peripheral immune tolerance form, in which, mature lymphocytes in lymphoid tissues associated with mucosa, become non-functional or hypo responsive due to prior oral administration of antigen. OT is an important immunological phenomenon due to its therapeutic potential in inflammatory processes and others diseases. Here we evaluated leukotriene role […]
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Anti-inflammatory properties of menthol and menthone in Schistosoma mansoni infection

  • Authors: Afonso A, Allegretti SM, Anibal FF, Cagnazzo TDO, Faccioli LH, Feitosa KA, Soares EG, Zaia MG
  • Publication Year: 2016
  • Journal: Frontiers in Pharmacology
  • Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911957/

Schistosomiasis is a parasitic disease caused by several species of trematode worms and it is believed that more than 261 million people are affected worldwide. New drug development has become essential because there is a risk of the parasite becoming resistant to Praziquantel, the only drug available for this infection. This study evaluated parasitological, immunological […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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