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Home / Archives for 2019

Whole-genome characterization of G12 rotavirus strains detected in Mozambique reveals a co-infection with a GXP[14] strain of possible animal origin.

  • Authors: Strydom A, Motanyane L, Nyaga MM, João ED, Cuamba A, Mandomando I, Cassocera M, de Deus N
  • Publication Year: 2019
  • Journal: Journal of General Virology
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/31140967

A high prevalence of G12 rotavirus strains has previously been reported in southern Mozambique. In this study, the full genomes of five Mozambican G12 strains were determined directly from stool using an Illumina Miseq platform. One sample (0060) contained an intergenogroup co-infection of a G12P[8] Wa-like strain and a GXP[14] DS-1-like strain. The sequences of […]
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Liaisons dangereuses: Cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito aedes aegypti from Brazil and French Guiana

  • Authors: Salgueiro P, Restrepo-Zabaleta J, Costa M, Galardo AKR, Pinto J, Gaborit P, Guidez A, Martins AJ, Dusfour I
  • Publication Year: 2019
  • Journal: Memórias do Instituto Oswaldo Cruz
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/31553370

BACKGROUND: In recent years, South America has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and Zika. Aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. OBJECTIVES: In order to improve vector control it is essential to study mosquito population genetics […]
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Prevalence of gonorrhea and chlamydia in a community clinic for men who have sex with men in Lisbon, Portugal

  • Authors: Ribeiro S, de Sousa D, Medina D, Castro R, Lopes A, Rocha M
  • Journal: International journal of STD & AIDS
  • Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6732818/

Men who have sex with men (MSM) are at greater risk for sexually transmitted infections (STIs). Data on MSM chlamydia and gonorrhea prevalence estimates and associated risk factors are scarce. To our knowledge, this is the first study to describe the prevalence and the determinants of both chlamydia and gonorrhea infections in MSM in Portugal. […]
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The contribution of efflux pumps in mycobacterium abscessus complex resistance to clarithromycin

  • Authors: Vianna JS, Machado D, Ramis IB, Silva FP, Bierhals DV, Abril MA, von Groll A, Ramos DF, Lourenço MCS, Viveiros M, da Silva PEA
  • Publication Year: 2019
  • Journal: Antibiotics
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/31540480

The basis of drug resistance in Mycobacterium abscessus is still poorly understood. Nevertheless, as seen in other microorganisms, the efflux of antimicrobials may also play a role in M. abscessus drug resistance. Here, we investigated the role of efflux pumps in clarithromycin resistance using nine clinical isolates of M. abscessus complex belonging to the T28 erm(41) sequevar responsible for the inducible resistance […]
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Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum

  • Authors: Cá B, Fonseca KL, Sousa J, Maceiras AR, Machado D, Sanca L, Rabna P, Rodrigues PNS, Viveiros M, Saraiva M
  • Publication Year: 2019
  • Journal: Frontiers in Microbiology
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/31552007

Tuberculosis remains a public health problem and a main cause of death to humans. Both Mycobacterium tuberculosis and Mycobacterium africanum cause tuberculosis. In contrast to M. tuberculosis, which is geographically spread, M. africanum is restricted to West Africa. Differences have also been found in the growth rate and type of disease caused by M. africanum, globally suggesting an attenuation of this bacteria. In […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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