Liaisons dangereuses: Cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito aedes aegypti from Brazil and French Guiana

Authors: Salgueiro P, Restrepo-Zabaleta J, Costa M, Galardo AKR, Pinto J, Gaborit P, Guidez A, Martins AJ, Dusfour I
Publication Year: 2019
Journal: Memórias do Instituto Oswaldo Cruz
Link: https://www.ncbi.nlm.nih.gov/pubmed/31553370

BACKGROUND: In recent years, South America has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and Zika. Aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. OBJECTIVES: In order to improve vector control it is essential to study mosquito population genetics […]
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Structure of hierridin c, synthesis of hierridins b and c, and evidence for prevalent alkylresorcinol biosynthesis in picocyanobacteria

Authors: Costa M, Sampaio-Dias IE, Castelo-Branco R, Scharfenstein H, Rezende de Castro R, Silva A, Schneider MPC, Araújo MJ, Martins R, Domingues VF, Nogueira F, Camões V, Vasconcelos VM, Leão PN
Publication Year: 2019
Journal: Journal of Natural Products
Link: https://www.ncbi.nlm.nih.gov/pubmed/30715888

Small, single-celled planktonic cyanobacteria are ubiquitous in the world’s oceans yet tend not to be perceived as secondary metabolite-rich organisms. Here we report the isolation and structure elucidation of hierridin C, a minor metabolite obtained from the cultured picocyanobacterium Cyanobium sp. LEGE 06113. We describe a simple, straightforward synthetic route to the scarcely produced hierridins […]
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Mosquito Akirin as a potential antigen for malaria control

Authors: Costa M, Custodio, de la Fuente J, Domingos A, Moreno-Cid JA, Pinheiro-Silva R, Silveira H, Villar M
Publication Year: 2014
Journal: Malaria Journal
Link: http://www.malariajournal.com/content/13/1/470

Recent evidences using Subolesin (SUB) and Akirin (AKR) vaccines showed a reduction in the survival and/or fertility of blood-sucking ectoparasite vectors and the infection with vector-borne pathogens. These experiments suggested the possibility of using AKR for malaria control.
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Liaisons dangereuses: Cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito aedes aegypti from Brazil and French Guiana

Structure of hierridin c, synthesis of hierridins b and c, and evidence for prevalent alkylresorcinol biosynthesis in picocyanobacteria

Mosquito Akirin as a potential antigen for malaria control

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