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Home / Archives for 2016

Follow-up on commitments at the Third Global Forum on Human Resources for Health: Indonesia, Sudan, Tanzania.

  • Authors: Badr E, Cometto G, Dussault G, Haroen H, Mapunda M, Mars AST, Pritasari K
  • Publication Year: 2016
  • Journal: Human Resources for Health
  • Link: https://human-resources-health.biomedcentral.com/articles/10.1186/s12960-016-0112-0%20

Commitments at the Third Global Forum on Human Resources for Health The authors assess the commitments made at the Third Global Forum on Human Resources for Health (HRH) by Indonesia, Sudan, and Tanzania, to implement health workforce plans. The authors conducted a study through published and gray literature in English and field research with focal points […]
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Sub-Epidemics Explain Localized High Prevalence of Reduced Susceptibility to Rilpivirine in Treatment-Naive HIV-1-Infected Patients: Subtype and Geographic Compartmentalization of Baseline Resistance Mutations

  • Authors: Abecasis AB, Baele G, Camacho RJ, Gomes P, Pineda-Peña AC, Theys K, Van Laethem K, Vandamme AM
  • Publication Year: 2016
  • Journal: AIDS Research and Human Retroviruses
  • Link: https://www.liebertpub.com/doi/abs/10.1089/aid.2015.0095%20

The latest nonnucleoside reverse transcriptase inhibitor (NNRTI) rilpivirine (RPV) is indicated for human immunodeficiency virus type-1 (HIV-1) patients initiating antiretroviral treatment, but the extent of genotypic RPV resistance in treatment-naive patients outside clinical trials is poorly defined. This retrospective observational study of clinical data from Belgium and Portugal evaluates genotypic information from HIV-1 drug-naive patients […]
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Pharmaceutical services cost analysis using time-driven activity-based costing: A contribution to improve community pharmacies’ management.

  • Authors: Gregório J, Lapão L, Russo G
  • Publication Year: 2016
  • Journal: Research in Social and Administrative Pharmacy
  • Link: http://linkinghub.elsevier.com/retrieve/pii/S1551741115001588%20

The current financial crisis is pressing health systems to reduce costs while looking to improve service standards. In this context, the necessity to optimize health care systems management has become an imperative. However, little research has been conducted on health care and pharmaceutical services cost management. Pharmaceutical services optimization requires a comprehensive understanding of resources […]
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Fluorimetric methods for analysis of permeability, drug transport kinetics, and inhibition of the ABCB1 membrane transporter

  • Authors: Amaral L, Armada A, Martins C, Molnar J, Rodrigues AS, Spengler G, Viveiros M
  • Publication Year: 2016
  • Journal: Cancer Drug Resistance
  • Link: https://link.springer.com/protocol/10.1007%2F978-1-4939-3347-1_7%20

The cell membrane P-glycoprotein (P-gp; MDR1, ABCB1) is an energy-dependent efflux pump that belongs to the ATP-binding cassette (ABC) family of transporters, and has been associated with drug resistance in eukaryotic cells. Multidrug resistance (MDR) is related to an increased expression and function of the ABCB1 (P-gp) efflux pump that often causes chemotherapeutic failure in […]
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First isolates of Leptospira spp, from rodents captured in Angola

  • Authors: Carreira T, Fortes-Gabriel E, Vieira ML
  • Publication Year: 2016
  • Journal: American Journal of Tropical Medicine and Hygiene
  • Link: http://www.ajtmh.org/content/journals/10.4269/ajtmh.15-0027

Rodents play an important role in the transmission of pathogenic Leptospira spp. However, in Angola, neither the natural reservoirs of these spirochetes nor leptospirosis diagnosis has been considered. Regarding this gap, we captured rodents in Luanda and Huambo provinces to identify circulating Leptospira spp. Rodent kidney tissue was cultured and DNA amplified and sequenced. Culture […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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