GHTM

Global Health and Tropical Medicine

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Home / Archives for 2021

Probing the Rhipicephalus bursa sialomes in potential anti-tick vaccine candidates: A reverse vaccinology approach

  • Authors: Joana Couto, Gonçalo Seixas, Christian Stutzer, Nicholas A Olivier, Christine Maritz-Olivier, Sandra Antunes, Ana Domingos
  • Publication Year: 2021
  • Journal: Biomedicines, 9(4), art 363
  • Link: https://doi.org/10.3390/biomedicines9040363

ABSTRACT In the wake of the ‘omics’ explosion of data, reverse vaccinology approaches are being applied more readily as an alternative for the discovery of candidates for next generation diagnostics and vaccines. Promising protective antigens for the control of ticks and tick-borne diseases can be discovered by mining available omics data for immunogenic epitopes. The […]
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Prevalence and genome characterization of porcine rotavirus A in southern Mozambique

  • Authors: Simone S Boene, Eva D João, Amy Strydom, Benilde Munlela, Assucênio Chissaque, Adilson Fernando Loforte Bauhofer, Elvino Nabetse, Dalilo Latifo, Aida Cala, Lourenço Mapaco, Jorfélia Chilaúle, Hester G O'Neill, Nilsa de Deus
  • Publication Year: 2021
  • Journal: Infection, Genetics and Evolution, vol 87, art 104637
  • Link: https://doi.org/10.1016/j.meegid.2020.104637

ABSTRACT Rotavirus A (RVA) is an important pathogen causing gastroenteritis in many species, including humans and pigs. The objective of this study was to determine the prevalence of RVA in pigs from smallholdings and commercial farms in southern Mozambique and characterize the complete genomes of selected strains. RVA was detected at a rate of 11.8% (n = 288), […]
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Preliminary comparative analysis of the resolving power of COX1 and 16S-rDNA as molecular markers for the identification of ticks from Portugal

  • Authors: Diogo Filipe, Ricardo Parreira, André Pereira, Nuno Galvão, José Manuel Cristóvão, Mónica Nunes, Maria Luísa Vieira, Lenea Campino, Carla Maia
  • Publication Year: 2021
  • Journal: Veterinary Parasitology: Regional Studies and Reports, vol 24, art 100551
  • Link: https://doi.org/10.1016/j.vprsr.2021.100551

REGIONAL REPORT ABSTRACT The utility of mitochondrial cytochrome oxidase subunit I (COX1) and 16S ribosomal DNA (16S-rDNA) sequence analyses as a complementary/alternative tool to classical taxonomy, for the identification of some of the most prevalent hard tick species from Portugal was evaluated using BOLD-ID (COX1 only), BLASTn and phylogenetic tree reconstruction based on multiple nucleotide sequence […]
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Pneumocystis pneumonia in the COVID-19 pandemic era: similarities and challenges

  • Authors: Magdalena Szydłowicz, Olga Matos
  • Publication Year: 2021
  • Journal: Trends in Parasitology, 37(10), pp 859 - 862
  • Link: https://doi.org/10.1016/j.pt.2021.07.010

FORUM The clinical picture of the fungal disease, Pneumocystis pneumonia, resembles the course of coronavirus disease 2019 (COVID-19), presenting a diagnostic challenge in the pandemic era. We discuss the concern of Pneumocystis jirovecii and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coinfection, their similarities, and the impact of immunosuppression, with a suggested diagnostic pathway for their suspected coinfection.   KEYWORDS Pneumocystis jirovecii; pneumonia; SARS-CoV-2; COVID-19.
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Phenotypic and Molecular Traits of Staphylococcus coagulans Associated with Canine Skin Infections in Portugal

  • Authors: Sofia Santos Costa, Valéria Oliveira, Maria Serrano, Constança Pomba, Isabel Couto
  • Publication Year: 2021
  • Journal: Antibiotics, 10(5), art 518
  • Link: https://doi.org/10.3390/antibiotics10050518

Antibiotics 2021, 10(5), 518;
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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Funding

UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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