GHTM

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Home / Archives for Arez AP

Analysis of malaria associated genetic traits in Cabo Verde, a melting pot of European and sub Saharan settlers

  • Authors: Alves J, Amorim A, Arez AP, Faustino P, Gonçalves N, Gusmão L, Manco L, Silva J, Do Rosário VE, Ribeiro L, Machado P
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Analysis+of+malaria+associated+genetic+traits+in+Cabo+Verde%2C+a+melting+pot+of+European+and+sub+Saharan+settlers

Malaria has occurred in the Cabo Verde archipelago with epidemic characteristics since its colonization. Nowadays, it occurs in Santiago Island alone and though prophylaxis is not recommended by the World Health Organization, studies have highlight the prospect of malaria becoming a serious public health problem as a result of the presence of antimalarial drug resistance associated with mutations in the parasite populations and underscore the need for tighter surveillance.
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Mosquito fauna on the Cape Verde Islands (West Africa): an update on species distribution and a new finding

  • Authors: Alves J, Arez AP, Gomes B, Rodrigues R, Silva J, Sousa CA
  • Journal: Journal of Vector Ecology: Journal of the Society for Vector Ecology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Mosquito+fauna+in+Cape+Verde+islands+(West+Africa)%3A+an+update+on+species+distribution+and+a+new+finding

To evaluate the risk of transmission of vector-borne diseases, regular updates of the geographic distribution of insect vectors are required. In the archipelago of Cape Verde, nine mosquito species have been reported.
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Plasmodium vivax in the Democratic Republic of East Timor: Parasite prevalence and antifolate resistance-associated mutations

  • Authors: Arez AP, Cravo P, de Almeida A, Henriques G, Rosário VE
  • Journal: Acta Tropica
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Plasmodium+vivax+in+the+Democratic+Republic+of+East+Timor%3A+Parasite+prevalence+and+antifolate+resistance-associated+mutations

In the Democratic Republic of East Timor, Plasmodium falciparum and Plasmodium vivax malaria coexist, but limited information is available about the latter species.
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Malaria epidemiology in the Democratic Republic of East Timor

  • Authors: Arez AP, Cravo P, de Almeida A, Do Rosário VE
  • Journal: Asian Pacific Journal of Tropical Medicine
  • Link: https://www.sciencedirect.com/science/article/pii/S1995764510600697

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Duffy negative antigen is no longer a barrier to Plasmodium vivax–molecular evidences from the African West Coast (Angola and Equatorial Guinea)

  • Authors: Arez AP, Benito A, Berzosa P, Cano J, de Sousa B, Dias F, Do Rosário VE, Figueiredo J, Mendes C, Mora VG
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Duffy+negative+antigen+is+no+longer+a+barrier+to+Plasmodium+vivax+%E2%80%93+molecular+evidences+from+the+African+west+coast+(Angola+and+Equatorial+Guinea).

Plasmodium vivax shows a small prevalence in West and Central Africa due to the high prevalence of Duffy negative people. However, Duffy negative individuals infected with P. vivax have been reported in areas of high prevalence of Duffy positive people who may serve as supply of P. vivax strains able to invade Duffy negative erythrocytes. We investigated the presence of P. vivax in two West African countries, using blood samples and mosquitoes collected during two on-going studies.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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