Human lagochilascariasis – A rare helminthic disease

Authors: Barbosa AP, Campos DMB, Cravo P, Oliveira JAD, Ostermayer AL, Tavares GG
Publication Year: 2017
Journal: Plos Neglected Tropical Diseases
Link: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005510%20

Lagochilascariasis is a parasitic disease caused by a helminth of the order Ascaroidea, genus Lagochilascaris that comprises 6 species, among which only Lagochilascaris minor Leiper, 1909, is implicated in the human form of the disease. It is remarkable that the majority of cases of human lagochilascariasis in the Americas have been reported in Brazil. The […]
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On the ordeal of quinolone preparation via cyclisation of aryl-enamines; Synthesis and structure of ethyl 6-methyl-7-iodo-4-(3-iodo-4-methylphenoxy)-quinoline-3-carboxylate

Authors: Brás EM, Cristiano MLS, Fausto R, Henriques MSC, Horta P, Murtinheira F, Nogueira F, O'Neill PM, Paixão JA
Publication Year: 2017
Journal: Pure and Applied Chemistry
Link: https://www.degruyter.com/view/j/pac.2017.89.issue-6/pac-2016-1119/pac-2016-1119.xml

Recent studies directed to the design of compounds targeting the bc1 protein complex of Plasmodium falciparum, the parasite responsible for most lethal cases of malaria, identified quinolones (4-oxo-quinolines) with low nanomolar inhibitory activity against both the enzyme and infected erythrocytes. The 4-oxo-quinoline 3-ester chemotype emerged as a possible source of potent bc1 inhibitors, prompting us to expand the library of available […]
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Measuring depressive symptoms during adolescence: what is the role of gender?

Authors: Bulhões C, Ramos E, Severo M, Dias S, Barros H
Publication Year: 2017
Journal: Epidemiology and Psychiatric Sciences
Link: https://www.cambridge.org/core/journals/epidemiology-and-psychiatric-sciences/article/measuring-depressive-symptoms-during-adolescence-what-is-the-role-of-gender/B3F8E8E1A14C74324744599BBCBE363D

The higher prevalence of depressive symptoms among females is well recognised but the reasons for this gender difference are not fully understood. There is growing evidence that current diagnostic criteria and instruments used to assess depression are less sensitive to depression in men, but studies about this issue among adolescents are scarce, especially in Latin […]
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Respiratory microbiota and lower respiratory tract disease

Authors: Bassat Q, Lanaspa M, Medeiros MM, Muñoz-Almagro C
Publication Year: 2017
Journal: Expert Review of Anti-infective Therapy
Link: https://www.tandfonline.com/doi/abs/10.1080/14787210.2017.1349609?journalCode=ierz20

The respiratory airways harbor a complex succession of ecological niches with distinct but related bacterial communities. Particular challenges of respiratory microbiome research have led to limited scientific output compared to other human microbiomes. Areas covered: In this review, we summarize the current state of knowledge of the bacterial respiratory microbiome, with a particular focus on […]
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Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans

Authors: Corbel V, David JP, Dusfour I, Koou SY, Martins AJ, Moyes CL, Ng LC, Pinto J, Raghavendra K, Vincent Corbel, Vontas J, Weetman D
Publication Year: 2017
Journal: Plos Neglected Tropical Diseases
Link: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005625

Both Aedes aegytpi and Ae. albopictus are major vectors of 5 important arboviruses (namely chikungunya virus, dengue virus, Rift Valley fever virus, yellow fever virus, and Zika virus), making these mosquitoes an important factor in the worldwide burden of infectious disease. Vector control using insecticides coupled with larval source reduction is critical to control the transmission of these viruses to […]
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Human lagochilascariasis – A rare helminthic disease

On the ordeal of quinolone preparation via cyclisation of aryl-enamines; Synthesis and structure of ethyl 6-methyl-7-iodo-4-(3-iodo-4-methylphenoxy)-quinoline-3-carboxylate

Measuring depressive symptoms during adolescence: what is the role of gender?

Respiratory microbiota and lower respiratory tract disease

Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans

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